ArticleCureus2025
Pericardial Calcification Following Acute Myopericarditis After Initial CHOP Treatment for Mantle Cell Lymphoma: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
A 56-year-old woman with B-cell lymphoma underwent chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP). Within 30 hours, the patient developed acute cardiotoxicity, characterized by elevated cardiac enzymes and ST-segment and T-wave (ST-T) changes on electrocardiogram (ECG), despite normal echocardiographic findings. Both ST elevations and enzyme levels spontaneously improved the following day. One week later, computed tomography (CT) revealed a newly developed high-density area on the pericardium, suggestive of early calcific deposition, which was confirmed to have progressed on follow-up imaging. While anthracycline-related cardiovascular toxicities are well documented, this case demonstrates a rare and rapid evolution from acute myopericarditis to early pericardial calcification following initial CHOP therapy. This rare presentation of early-onset cardiotoxicity in a patient with B-cell lymphoma is discussed with reference to the existing literature.
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