ArticleCureus2025
From Chronic Anemia to Total Gastrectomy: A Case Report on a Challenging Form of Ménétrier's Disease.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Ménétrier's disease (MD) is a rare hypertrophic gastropathy marked by enlarged gastric folds, excessive mucus secretion, and protein-losing enteropathy. We present the case of a 25-year-old man initially hospitalized with severe chronic anemia, which revealed a rare and challenging form of MD. The patient reported persistent epigastric pain, vomiting, and recurrent hematemesis. Biological workup showed profound hypoalbuminemia (20 g/L) and microcytic anemia (Hb 5.8 g/dL, ferritin 3 ng/mL). Abdominal CT and upper endoscopy revealed massive polypoid thickening of the gastric fundus with cerebral-like folds and friable polypoid lesions. Histology confirmed foveolar hyperplasia with glandular atrophy, consistent with MD, in the absence of
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