Evidence map›Paper›PMID 40861637›Full record

ArticleCureus2025

Advances in Fracture Fixation: Enhancing Stability and Promoting Healing.

Muhammad Rizwan Umer, Areeba Asghar, Muhammad Abu Zar Nawaz, Fokehah Maryam, Safeer Ahmad Javid, Muddasir Reyaz Hassan, Amna Akbar, Areeba Zahid, Mariam K

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Muhammad Rizwan UmerTrauma Surgery, Royal Sussex County Hospital, Brighton, GBR.
Areeba AsgharMedicine and Surgery, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, GBR.
Muhammad Abu Zar NawazMedicine and Surgery, Royal Devon Healthcare NHS Foundation Trust, England, GBR.
Fokehah MaryamMedicine and Surgery, Tehsil Headquarters Hospital, Bhalwal, PAK.
Safeer Ahmad JavidTrauma Surgery, Royal Sussex County Hospital, Brighton, GBR.
Muddasir Reyaz HassanMedicine and Surgery, Northwick Park Hospital, London, GBR.
Amna AkbarEmergency and Accident, Abbas Institute of Medical Sciences, Muzaffarabad, PAK.
Areeba ZahidMedicine and Surgery, Faisalabad Medical University, Faisalabad, PAK.
Mariam KMedicine and Surgery, Hamdard University, Karachi, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancements in fracture fixation have significantly reshaped orthopedic trauma management by improving mechanical stability and promoting biological healing. This retrospective observational study assessed clinical and biomechanical outcomes in 500 patients who underwent surgical fixation for radiologically confirmed fractures. Patients were categorized into two groups: Group A received conventional fixation methods (e.g., standard plates and screws), while Group B was treated with advanced systems, including locking plates, intramedullary nails, minimally invasive percutaneous osteosynthesis (MIPO), and bioresorbable implants. Data analysis included 50 variables spanning demographics, clinical profiles, imaging, laboratory results, implant details, and postoperative outcomes. Statistical methods such as t-tests, chi-square, Mann-Whitney U, Kruskal-Wallis, Kaplan-Meier survival analysis, and multiple regression models were performed using IBM SPSS Statistics for Windows, Version 27.0 (Released 2019; IBM Corp., Armonk, NY, US). The study found that advanced fixation techniques resulted in significantly faster healing (12.4 vs. 14.9 weeks, p < 0.001), earlier mobilization (p = 0.003), and better three-month functional outcomes, with 80.1% in Group B achieving good to excellent recovery compared to 58.2% in Group A (p < 0.001). The complication rate was notably lower in the advanced group (10.8% vs. 20.4%, p = 0.003). Regression analysis identified implant type, vitamin D levels, and diabetes status as key predictors of healing duration, complication risk, and functional recovery. Predictive models demonstrated strong performance: a linear regression model for healing time (R² = 0.38, p < 0.001), a logistic regression model for complications (accuracy = 71.6%), and an ordinal regression model for functional outcomes (Nagelkerke R² = 0.41, p < 0.001). These findings support the clinical benefits of modern fixation systems and highlight the importance of integrating biomechanical choices with patient-specific health indicators to enhance fracture management outcomes.

Indexed as

bioresorbable implantsbone healingfracture fixationintramedullary nailslocking platesorthopedic surgeryosteoporosis

Identifiers

PMID40861637
PMCPMC12374596

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.