Evidence map›Paper›PMID 40861628›Full record

ArticleCureus2025

Real-World Outcomes of Biologic Therapy for Severe Asthma in a High-Burden Urban Population.

Justin Louie, Anandu M Anto, Sindhaghatta Venkatram, Charnicia Huggins, Gilda Diaz-Fuentes

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Justin LouiePharmacy, BronxCare Health System, Bronx, USA.
Anandu M AntoInternal Medicine, BronxCare Health System, Bronx, USA.
Sindhaghatta VenkatramPulmonary and Critical Care, BronxCare Health System, Bronx, USA.
Charnicia HugginsPharmacy, BronxCare Health System, Bronx, USA.
Gilda Diaz-FuentesPulmonary and Critical Care, BronxCare Health System, Bronx, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Asthma prevalence and mortality are disproportionately higher in underserved areas such as the Bronx compared to other regions of New York City. Biologic therapy is recommended for severe asthma but may present challenges in access and adherence among patients in low-resource settings. This study evaluates the real-world effectiveness and feasibility of biologic therapy in an inner-city cohort. Methods We conducted a retrospective cohort study of adult patients with severe asthma treated at an urban outpatient pulmonary and allergy clinic. Patients who received biologic therapy for at least six months between January 2020 and August 2023 were included. Outcome measures included Asthma Control Test (ACT) scores, asthma exacerbation rates, oral corticosteroid (OCS) use, lung function (forced expiratory volume in one second (FEV

Indexed as

asthma managementbiologic therapyinner-city hospitalreal-world evidencesevere asthma

Identifiers

PMID40861628
PMCPMC12375387

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.