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ArticleWellcome open research2025

Case Report: Genetic evolution of

Terry John Evans, Chantisa Keeratipusana, Anousone Douangnouvong, Vilayouth Phimolsarnnousith, Davanh Sengdatka, Ko Chang, Koukeo Phommasone, Claire Chewapreecha, Elizabeth A Ashley, Elizabeth M Batty

Abstract readCase Reports
In one paragraph

Article in Wellcome open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Case Report: Genetic evolution ofWellcome open research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Terry John EvansLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.ORCID https://orcid.org/0000-0001-8976-5197
Chantisa KeeratipusanaFaculty of Tropical Medicine, Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0008-1651-0204
Anousone DouangnouvongLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.
Vilayouth PhimolsarnnousithLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.ORCID https://orcid.org/0000-0001-8180-0007
Davanh SengdatkaLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.
Ko ChangInfectious Diseases Department, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.
Koukeo PhommasoneLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.
Claire ChewapreechaFaculty of Tropical Medicine, Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
Elizabeth A AshleyLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao People's Democratic Republic.ORCID https://orcid.org/0000-0002-7620-4822
Elizabeth M BattyFaculty of Tropical Medicine, Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-8559-452X

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: Melioidosis is a significant yet neglected cause of sepsis in tropical regions, particularly in southeast Asia, with poor clinical outcomes. It is a growing threat with an expanding global footprint. The causative organism, Case presentation: A 60-year-old farmer presented in septic shock to a hospital in Laos, and Conclusions: Mutations in

Indexed as

antimicrobial resistanceBurkholderia pseudomalleiLao PDRmelioidosissepsissoutheast Asia

Identifiers

PMID40861388
PMCPMC12374155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.