Evidence map›Paper›PMID 40861246›Full record

ArticleNpj Materials degradation2025

Effects of natural aging on hydrophilicity and mechanical properties of PDMS in various storage environments.

Shuyu Zhang, Anne E Staples

Abstract read
In one paragraph

Article in Npj Materials degradation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shuyu ZhangVirginia Tech-Wake Forest School of Biomedical Engineering and Sciences, Blacksburg, VA USA.ORCID 0009-0000-6557-8012
Anne E StaplesVirginia Tech-Wake Forest School of Biomedical Engineering and Sciences, Blacksburg, VA USA.ORCID 0000-0003-4823-8184

Funding

A pulse-driven micropump for continuous drug deliveryR21EB035655 · NIBIB · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Anne Staples · 2024 to 2026
$550k
NIBIB NIH HHS R21 EB035655
6 · The paper itself

Abstract

Polydimethylsiloxane (PDMS) is a synthetic elastomer widely used in biomedical and industrial applications. Despite its widespread use, the natural evolution of its mechanical and surface properties over time remains poorly understood. In this study, we fabricated PDMS samples with base-to-curing agent mixing ratios from 5:1 to 30:1 and aged them for up to 8 weeks under six non-harsh conditions at room temperature. Contact angle measurements revealed increasing hydrophobicity with aging, with maximum increases up to 16.5°. Mechanical testing showed up to 130% increases in Young's modulus and 60% changes in flexibility after 5 weeks. Storage in mineral oil best preserved surface hydrophilicity, while storage in water best maintained mechanical integrity. These results provide a framework for optimizing PDMS storage conditions in microfluidic and biomedical device applications.

Indexed as

BiomaterialsBiomedical engineeringEngineeringMaterials for devicesMaterials scienceMechanical engineeringSoft materials

Identifiers

PMID40861246
PMCPMC12370534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.