Evidence map›Paper›PMID 40861056›Full record

ArticleFrontiers in pediatrics2025

The expression pattern and role of circulating CXCR5

Jian-Yong Wang, Yi Xin, Xiao-Li Wang, Lin-Lin Li, Ai-Min Li, Xiao-Lu Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jian-Yong Wang *Department of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China.
Yi Xin *Department of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China.
Xiao-Li WangDepartment of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China.
Lin-Lin LiDepartment of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China.
Ai-Min LiDepartment of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China.
Xiao-Lu ZhangDepartment of Clinical Laboratory, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Immune thrombocytopenia (ITP) is the most common bleeding disorder in children. Tfh cells play a crucial role in the pathogenesis of ITP by promoting the production of anti-platelet autoantibodies. Recent studies have shown that CXCR5 Methods: A total of 96 children with nITP and 48 healthy children were enrolled in this study. FCM was used to compare the frequencies of circulating CXCR5 Results: Compared with healthy controls, the frequency of circulating CXCR5 Conclusions: The excessive activation and proliferation of CXCR5

Indexed as

childrenCXCR5+γδ T cellsimmune thrombocytopenianewly diagnosedTfh cells

Identifiers

PMID40861056
PMCPMC12375633

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.