Evidence map›Paper›PMID 40861038›Full record

ArticleHorticulture research2025

Sorbitol promotes the graft healing process in pears.

Jianlong Liu, Baoyi Wang, Siying Zhang, Min Liu, Wankun Liu, Ping Yang, Chenglin Liang, Jiankun Song, Yingjie Yang, Ran Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Horticulture research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jianlong LiuQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Baoyi WangQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Siying ZhangQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Min LiuQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Wankun LiuQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Ping YangQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Chenglin LiangHaidu College, Qingdao Agricultural University, No. 11, Wenhua Road, Laiyang City, Shandong Province, 265200, China.
Jiankun SongQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Yingjie YangQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Ran WangQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.
Dingli LiQingdao Key Lab of Genetic Improvement and Breeding of Horticultural Plants, College of Horticulture, Qingdao Agricultural University, No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province 266109, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pear propagation is primarily achieved through asexual reproduction via grafting. During the graft union healing process, there is metabolic exchange between the rootstock and the scion. However, a multi-omics systematic study on the role of sugar in the graft union healing process has not been reported. In this study, using micrografting techniques, we comparatively analyzed the metabolic changes during the healing process in homograft and heterograft of pear through metabolomics and transcriptomics. We found significant differences in sugar metabolism pathways after grafting. In the fructose and mannose metabolic pathways, sorbitol exhibited opposite trends in homograft and heterograft. Subsequent transcriptomics analysis confirmed that these metabolite changes were caused by differential expression of related synthetic and converting enzyme genes. Furthermore, spatial metabolomics identified sorbitol accumulation in the scion after homologous grafting. To further verify the role of sorbitol, exogenous sorbitol treatment was applied, revealing that it enhanced tissue adhesion, shortened the time required for callus growth, promoted high expression of xylem formation genes and cambium differentiation genes, and facilitated the reconnection of xylem and phloem, thereby playing a positive role in graft union healing. This study systematically analyzed changes in sugar metabolism during the grafting process and confirmed that sorbitol can promote graft union healing.

Identifiers

PMID40861038
PMCPMC12373972

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.