Evidence map›Paper›PMID 40861011›Full record

ReviewCell insight2025

Faithful inheritance: Parental histone recycling and epigenetic memory in fission yeast.

Yimeng Fang, Takenori Toda, Songtao Jia

Abstract readReview
In one paragraph

Review in Cell insight, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yimeng FangDepartment of Biological Sciences, Columbia University, New York, NY, 10027, USA.
Takenori TodaDepartment of Biological Sciences, Columbia University, New York, NY, 10027, USA.
Songtao JiaDepartment of Biological Sciences, Columbia University, New York, NY, 10027, USA.

Funding

Mechanism of heterochromatin assembly and oncogenic histone mutationsR35GM126910 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Songtao Jia · 2018 to 2026
$3.8M
NIGMS NIH HHS R35 GM126910
6 · The paper itself

Abstract

Accurate transmission of chromatin states during DNA replication is central to epigenetic inheritance. Recent advances have illuminated mechanisms by which parental histones, which carry key post-translational modifications, are recycled and redistributed to daughter strands. This review synthesizes emerging insights into the molecular machinery that mediates histone recycling during replication. It highlights the interplay between histone chaperones and replication factors and examines how perturbations in these pathways influence heterochromatin inheritance. The fission yeast serves as a powerful model for recent investigations, revealing new principles that are conserved across eukaryotes.

Indexed as

DNA replicationDpb3Dpb4Epigenetic inheritanceFACTMcm2Mrc1Parental histone

Identifiers

PMID40861011
PMCPMC12375253

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.