Evidence map›Paper›PMID 40860896›Full record

ArticleObesity science & practice2025

Effect of Glucagon-Like Peptide 1 Receptor Agonists on Obstructive Sleep Apnea.

Bei-Bei Qian, Yu-Jie Huang, Cai-Feng Yan, Shang-Yong Feng, Dun-Min She

Abstract read
In one paragraph

Article in Obesity science & practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bei-Bei QianNorthern Jiangsu People's Hospital Northern Jiangsu People's Hospital Affiliated to Yangzhou University Yangzhou Jiangsu China.
Yu-Jie HuangHuaian Cancer Hospital Huaian Jiangsu China.
Cai-Feng YanNorthern Jiangsu People's Hospital Northern Jiangsu People's Hospital Affiliated to Yangzhou University Yangzhou Jiangsu China.ORCID https://orcid.org/0000-0003-1127-0690
Shang-Yong FengNorthern Jiangsu People's Hospital Northern Jiangsu People's Hospital Affiliated to Yangzhou University Yangzhou Jiangsu China.
Dun-Min SheNorthern Jiangsu People's Hospital Northern Jiangsu People's Hospital Affiliated to Yangzhou University Yangzhou Jiangsu China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Glucagon-like peptide-1 receptor (GLP-1R) agonists are well-established therapies for obesity and type 2 diabetes mellitus (T2DM). Emerging evidence also suggests their potential role in managing obstructive sleep apnea (OSA). This study aimed to investigate the association between GLP-1R agonists and OSA using genetic evidence. Methods: Cis-expression quantitative trait loci (cis-eQTLs) associated with the Results: IVW analysis showed that genetically predicted GLP-1R agonist exposure was associated with a reduction in BMI ( Conclusion: This study provides genetic evidence supporting the protective role of GLP-1R agonists against OSA, highlighting their potential as a therapeutic strategy for OSA management.

Indexed as

GLP‐1R agonistsMendelian randomizationobesityobstructive sleep apneatype 2 diabetes

Identifiers

PMID40860896
PMCPMC12371556

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.