Evidence map›Paper›PMID 40860892›Full record

ArticleFamilies in society : the journal of contemporary human services2025

Trends in Prenatal Polysubstance Exposure.

Cynthia Nichols, Margaret Lloyd Sieger

Abstract read
In one paragraph

Article in Families in society : the journal of contemporary human services, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cynthia NicholsSchool of Social Work, University of Connecticut, Hartford, CT.
Margaret Lloyd SiegerSchool of Social Work, University of Connecticut, Hartford, CT.

Funding

Public Policy & Health for Substance Exposed Infant-Mother DyadsK01DA058060 · NIDA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Margaret Lloyd Sieger · 2023 to 2026
$702k
NIDA NIH HHS K01 DA058060
6 · The paper itself

Abstract

Researchers are referring to polysubstance use as the "fourth wave" of the opioid epidemic. Prenatal polysubstance exposure is on the rise, leading to increased health and safety complications among infants and caregivers. This study examined the co-occurrence of polysubstance exposures and child maltreatment concerns using Child Abuse and Prevention Treatment Act (CAPTA) notifications made in Connecticut. Sixteen percent of notifications included polysubstance exposures. The average total number of substances identified among polysubstance cases was 2.39 (range 2-7). Each additional substance identified was shown to have 2.5 times higher odds of maltreatment report controlling for maternal age, infant race/ethnicity, and toxicology test type. Findings from this study suggest that the total number of substances is a primary factor contributing to maltreatment reports among infants with prenatal substance exposure.

Indexed as

CAPTAChild MaltreatmentPrenatal Substance Exposure

Identifiers

PMID40860892
PMCPMC12373403

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.