SynthesisFrontiers in oncology2025
Heavy metal carcinogenicity: a scoping review of observational & experimental evidence.
Synthesis in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Combined Occupational Exposure to Lead and Other Metals and Risk of Lung Cancer.La Medicina del lavoro · 2026Article
- Metal carcinogens and cancer: integrating genetic and epigenetic perspectives.Frontiers in oncology · 2026Review
- Epigenetic regulation of the β-catenin pathway in cadmium-induced colorectal cancer progression and chemoresistance.Frontiers in cell and developmental biology · 2026Review
- Airborne metals and malignant pleural effusions: the role of oxidative stress.Frontiers in toxicology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental heavy metal pollutants are highly toxic and are usually of human origin. Studies have suggested a link between cadmium and arsenic carcinogenesis and geographical location. This review was conducted to explore the methodologies that have been used to determine the risk of carcinogenesis as it relates to cadmium & arsenic exposure as well as geographical location. A search of pertinent literature published up to December 2024 was conducted using the databases, PubMed, and EBSCO. The following MeSH terms were used primarily to search the databases, "heavy metals," "cadmium," "arsenic," "carcinogenesis," "malignancy," and "toxicity." Articles were removed if they were not closely related to the review topic. As evidenced in this review, there has been several research done over the years exploring the heavy metal exposure and the risk for carcinogenesis. The methodologies used to determine this risk are quite uniformed across the various studies. However, there is a paucity of studies dealing with the potential influence of geographical location in relation to the risk of carcinogenesis. This gap in knowledge shows that more work needs to be done to improve on the current knowledge of arsenic and cadmium and carcinogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.