ArticleFrontiers in oncology2025
Analysis of risk factors for postoperative recurrence of stage IA lung adenocarcinoma.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Significant improvement in overall survival with postoperative traditional Chinese medicine in stage I lung adenocarcinoma: a real-world retrospective cohort study.Translational lung cancer research · 2026Article
- Local Recurrence After Lung Segmentectomy-Risk Factors and Future Directions: A Contemporary Review.Cancers · 2026Review
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Authors and funding
7 authors.
Funding
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Abstract
Objective: To explore the influencing recurrence in patients with stage IA lung adenocarcinoma following surgical resection. Method: A retrospective analysis was conducted on the clinical and pathological data of patients with stage IA lung adenocarcinoma who underwent surgical resection in the Department of Thoracic Surgery at Tianjin Medical University General Hospital from January 1, 2018, to December 31, 2021. The Fine-Gray model was utilized for multivariate analysis to identify factors influencing the cumulative incidence of lung cancer recurrence. The hazard ratio (HR) and its 95% confidence interval (CI) were calculated. Result: Among 475 patients, there were 30 cases of postoperative recurrence and metastasis. The results of the univariate analysis using the Gray test indicated that vascular invasion, STAS, solid and micropapillary patterns, pTNM classification, lymph node resection method, surgical method, organizational differentiation, CTR had a significant impact (P<0.05). The multivariate analysis revealed that pTNM classification, lymph node resection method, vascular invasion and the presence of solid or micropapillary patterns were significantly correlated. Conclusion: Tumor staging, the presence of solid or micropapillary components in pathology, vascular invasion, and the method of lymph node resection significantly influence postoperative disease-free survival (DFS) in patients with stage IA lung adenocarcinoma undergoing surgical resection.
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