SynthesisFrontiers in oral health2025
Current perspectives and trend of ferroptosis in head and neck cancer: a bibliometric analysis.
Synthesis in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Global evolution of ferroptosis research: a comprehensive bibliometric analysis of publication trends, geographic patterns, pharmacological innovation, and translational progress from inception through 2025.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Ferroptosis, a form of regulated cell death driven by iron dependency, is also referred to as iron-mediated cell death. In recent years, ferroptosis has garnered considerable research interest as a distinct cell death mechanism, primarily characterized by excessive intracellular iron accumulation and the formation of lipid peroxides. Ferroptosis is intricately linked to the initiation and progression of a wide spectrum of diseases, notably cancers, neurodegenerative disorders-including Alzheimer's and Parkinson's diseases-and cardiovascular conditions. Despite growing interest in ferroptosis within cancer research, systematic analyses and comprehensive visualizations of research hotspots, leading contributors, and emerging trends-particularly in the context of head and neck cancers-remain limited. Materials and methods: This study conducted a bibliometric analysis using data retrieved from the Web of Science Core Collection, covering the period from January 1, 2016, to March 20, 2025. Bibliometric mapping and visualization were performed using VOSviewer and CiteSpace. Results: A total of 110 publications were identified across 19 countries. China contributed the highest number of publications (84 articles; 76.36%), followed by South Korea (14 articles; 12.73%) and the United States (6 articles; 5.46%). Conclusion: This study presents a comprehensive overview of recent trends and advances in ferroptosis research within the context of head and neck cancer, delineating key research frontiers and emerging thematic areas. The findings offer valuable insights and serve as a useful reference for researchers pursuing work in this domain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.