Evidence map›Paper›PMID 40860788›Full record

ArticleOxford medical case reports2025

Isolated syndrome of inappropriate antidiuresis (SIAD) after Transphenoidal surgery of a non-functioning pituitary adenoma: clinical case report.

Nasthia Quilismal, Mariana Risso, Patricia Agüero, Ramilo Lima, Francisco Garagorry, Dardo Centurion, Maria M Pineyro

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Nasthia QuilismalUnidad Académica de Endocrinología y Metabolismo, Hospital de Clínicas "Dr. Manuel Quíntela", Facultad de Medicina, Universidad de la República, Avenida Italia S/N, CP 11600, Montevideo, Uruguay.ORCID https://orcid.org/0000-0002-1231-9962
Mariana RissoUnidad Académica de Endocrinología y Metabolismo, Hospital de Clínicas "Dr. Manuel Quíntela", Facultad de Medicina, Universidad de la República, Avenida Italia S/N, CP 11600, Montevideo, Uruguay.
Patricia AgüeroUnidad Académica de Endocrinología y Metabolismo, Hospital de Clínicas "Dr. Manuel Quíntela", Facultad de Medicina, Universidad de la República, Avenida Italia S/N, CP 11600, Montevideo, Uruguay.
Ramilo LimaUnidad Académica de Neurocirugía, Hospital de Clínicas "Dr. Manuel Quintela", Facultad de Medicina, Universidad de la República, Avenida Italia S/N, CP 11600, Montevideo, Uruguay.
Francisco GaragorryUnidad Académica de Anatomía Patológica, Hospital de Clínicas "Dr. Manuel Quintela", Facultad de Medicina, Universidad de la República, Avenida Italia S/N, CP 11600, Montevideo, Uruguay.
Dardo CenturionUnidad Académica de Anatomía Patológica, Hospital de Clínicas "Dr. Manuel Quintela", Facultad de Medicina, Universidad de la República, Avenida Italia S/N, CP 11600, Montevideo, Uruguay.
Maria M PineyroUnidad Académica de Endocrinología y Metabolismo, Hospital de Clínicas "Dr. Manuel Quíntela", Facultad de Medicina, Universidad de la República, Avenida Italia S/N, CP 11600, Montevideo, Uruguay.ORCID https://orcid.org/0000-0003-2083-7839

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Disorders of water balance, including arginine vasopressin deficiency (AVP-D) and syndrome of inappropriate antidiuresis (SIAD), are common postoperative complications following pituitary surgery. While AVP-D typically occurs as an isolated condition, SIAD may also present independently. Clinical Case: We describe the case of a patient with a non-functioning pituitary adenoma who underwent transsphenoidal surgery. On postoperative day 7, she developed isolated SIAD, characterized by a plasma sodium level of 113 mmol/L, normovolemia, urine osmolality of 364 mOsm/kg, and urine sodium concentration of 50 mmol/L. A daily fluid restriction of 800 mL resulted in the resolution of hyponatremia within 48 h. Conclusions: Water balance disorders following pituitary surgery are often unpredictable. This case highlighs the importance of close postoperative clinical and biochemical monitoring. Vigilance is essential, even in the absence of AVP-D, to ensure early detection and management of potentially severe complications such as SIAD.

Indexed as

arginine vasopressin deficiencyhyponatremiasyndrome of inappropriate antidiuresistranssphenoidal surgery

Identifiers

PMID40860788
PMCPMC12375806

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