Evidence map›Paper›PMID 40860776›Full record

ReviewInternational journal of medical sciences2025

Effect of Pituitary-Target Gland Axis on RAAS in the Context of COVID-19.

Baofeng Wu, Ru Li, Qinhao Liu, Shuqing Jin, Hongxia Wei, Ming Xu, Yi Zhang, Yunfeng Liu

Abstract readReview
In one paragraph

Review in International journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Baofeng WuDepartment of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Ru LiDepartment of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Qinhao LiuDepartment of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Shuqing JinDepartment of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Hongxia WeiDepartment of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Ming XuDepartment of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Yi ZhangDepartment of Pharmacology, Shanxi Medical University, Taiyuan, 030001, China.
Yunfeng LiuDepartment of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pituitary gland is a very important endocrine gland in the human body. It secretes and releases many hormones crucial for controlling physiological processes, such as energy metabolism, human growth and development, and reproduction. The renin-angiotensin-aldosterone system regulates water and salt homeostasis, controlling blood pressure. Since the discovery of the renin-angiotensin-aldosterone system, exploring and studying its role in pathophysiology has never stopped, and patients have benefited from drug-based and clinical studies. This review focuses on the effects of the pituitary-target gland axis (pituitary-thyroid axis, pituitary-adrenal axis, pituitary-growth hormone axis, pituitary-gonadal axis) and some hormones secreted and stored by the pituitary gland on the RAAS. While considering that SARS-CoV-2 reinfection still occurs, we aim to provide new insights into water-electrolyte balance and blood pressure regulation.

Indexed as

COVID-19Pituitary GlandRenin-Angiotensin SystemAngiotensin-Converting Enzyme 2Arginine VasopressinEstrogensHumansPituitary HormonesSARS-CoV-2Angiotensin-Converting Enzyme 2Arginine VasopressinEstrogensPituitary HormonesCOVID-19Pituitary glandPituitary hormonesRenin-angiotensin-aldosterone systemSARS-CoV-2

Identifiers

PMID40860776
PMCPMC12375137

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.