Evidence map›Paper›PMID 40860599›Full record

ArticlePatient preference and adherence2025

Tracking Changes in Oral Health-Related Quality of Life Before, During, and After Radiotherapy in Tongue Squamous Cell Carcinoma: A Case Series.

Irna Sufiawati, Novi Indriyani, Imme Kris Wicaksono, Emailsa Denta

Abstract readCase Reports
In one paragraph

Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Irna SufiawatiDepartment of Oral Medicine, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java, Indonesia.ORCID 0000-0002-2506-5105
Novi IndriyaniOral Medicine Residency Program, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java, Indonesia.ORCID 0009-0002-9776-2142
Imme Kris WicaksonoOral Medicine Residency Program, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java, Indonesia.
Emailsa DentaDepartment of Radiology, Radiation Oncology Sub-Division, Dr. Hasan Sadikin Central General Hospital, Bandung, West Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tongue squamous cell carcinoma (TSCC) is the most common type of oral cancer. Effective and patient-centered management is essential to reduce mortality, improve survival, and enhance oral health-related quality of life (OHRQoL). Purpose: To assess OHRQoL and pain levels in TSCC patients across radiotherapy phases and the impact of supportive care on treatment adherence and patient well-being. Case Report: Four patients presented with painful, non-healing tongue ulcers of 4-8 months' duration and were referred to the Oral Medicine Clinic. All were diagnosed with TSCC and underwent radiotherapy. OHRQoL and pain levels were assessed using the oral health impact profile-14 (OHIP-14) and visual analogue scale (VAS), before, during, after radiotherapy. Common intraoral side effects included oral candidiasis, mucositis, and xerostomia, all of which impacted patients' comfort and adherence to ongoing treatment. Case Management: Management of radiotherapy-induced side effects included nystatin oral suspension, 0.025% hyaluronic acid mouthwash, diphenhydramine HCl, and artificial saliva gel. Individualized care plans were developed based on patient feedback and treatment tolerance. All patients demonstrated clinical improvement in oral lesions within 1-7 weeks. OHIP-14 and VAS scores improved before treatment (OHIP-14: 30-44; VAS: 9), during treatment (OHIP-14: 27-36; VAS: 8), and one month afterward (OHIP-14: 10-15; VAS: 1-5). Conclusion: The integration of proactive and personalized supportive oral care during radiotherapy can significantly improve OHRQoL and reduce pain levels, facilitating better treatment adherence and patient satisfaction. These findings support the importance of multidisciplinary collaboration and proactive symptom management in TSCC care.

Indexed as

OHIP-14oral canceroral complications of radiotherapyquality of life assessmentvisual analogue scale

Identifiers

PMID40860599
PMCPMC12375360

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.