Evidence map›Paper›PMID 40860597›Full record

ReviewBiology methods & protocols2025

Radiolabeling isolated mitochondria with Tc-99m: A first-in-field protocol and early feasibility findings.

Melanie Walker, Francisco Javier Miralles, Keiko Prijoles, Jacob S Kazmi, Jennifer Hough, David Lewis, Michael R Levitt, Yasemin Sancak

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biology methods & protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Melanie WalkerDepartment of Neurological Surgery, University of Washington, Seattle, WA, 98104, United States.ORCID https://orcid.org/0000-0002-8995-4657
Francisco Javier MirallesDepartment of Pharmacology, University of Washington, Seattle, WA, 98104, United States.
Keiko PrijolesDepartment of Neurological Surgery, University of Washington, Seattle, WA, 98104, United States.
Jacob S KazmiDonald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, 11549, United States.
Jennifer HoughDivision of Nuclear Medicine, University of Washington, Seattle, WA, 98104, United States.
David LewisDivision of Nuclear Medicine, University of Washington, Seattle, WA, 98104, United States.
Michael R LevittDepartment of Neurological Surgery, University of Washington, Seattle, WA, 98104, United States.ORCID https://orcid.org/0000-0003-3612-3347
Yasemin SancakDepartment of Pharmacology, University of Washington, Seattle, WA, 98104, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial transplantation is a promising but still experimental strategy for treating ischemic and metabolic disorders. A key barrier to its advancement is the lack of scalable, non-invasive methods for tracking transplanted extracellular mitochondria

Indexed as

electron microscopymitochondriamitochondrial transplantationradiopharmaceuticalsSPECTTechnetium-99m

Identifiers

PMID40860597
PMCPMC12371404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.