Evidence map›Paper›PMID 40860475›Full record

ArticleFrontiers in nutrition2025

The association between lutein and zeaxanthin intake and multi-level biological aging.

Meiyi Tao, Lin Zhang, Caidi Jiang, Jia Xiang, Shipeng Chen, Songwen Tan, Shengli Sun

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Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meiyi TaoHunan Provincial People's Hospital (First Affiliated Hospital of Hunan Normal University), Changsha, China.
Lin ZhangDepartment of Epidemiology and Preventive Medicine, The School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Caidi JiangXiangya School of Pharmaceutical Sciences, Central South University, Changsha, China.
Jia XiangHunan Pilot Free Trade Zone Global Cell Bank, Changsha, China.
Shipeng ChenHunan Pilot Free Trade Zone Global Cell Bank, Changsha, China.
Songwen TanSuzhou Industrial Park Monash Research Institute of Science and Technology, Suzhou, China.
Shengli SunHunan Provincial People's Hospital (First Affiliated Hospital of Hunan Normal University), Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study investigates the potential association between lutein and zeaxanthin (LZ) intake, particularly lutein, and biological aging. The study aims to explore how LZ intake affects the biological aging progression, particularly in organs like the liver, kidneys, and cardiovascular system, and explore the potential mechanism of lutein as the main carotenoid mediating this effect. Methods: We analyzed biological aging using biological age calculations based on data from the NHANES 2007-2015 database. Various adjusted models were used to assess the relationship between LZ intake and aging phenotypes. Transcriptome analysis was conducted to explore the potential mechanisms underlying the anti-aging effects of lutein. Results: A higher intake of LZ was associated with a slower biological aging rate ( Conclusion: Combined LZ intake is associated with attenuated multi-level biological aging [OR (95% CI): 0.93 (0.88, 0.93),

Indexed as

biological agingcarotenoidluteinNHANESzeaxanthin

Identifiers

PMID40860475
PMCPMC12370510

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.