Evidence map›Paper›PMID 40860399›Full record

ArticleIndian journal of thoracic and cardiovascular surgery2025

Outcomes of reoperative aortic valve surgery: data from a national registry over 23 years.

Pradeep Narayan, Arnaldo Dimagli, Jeremy Chan, Tim Dong, Charles Tan, Tugba Aydin, Daniel Paul Fudulu, Gianni Davide Angelini

Abstract read
In one paragraph

Article in Indian journal of thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pradeep NarayanNarayana Health, Bangalore, India.
Arnaldo DimagliBristol Heart Institute, Bristol Royal Infirmary, Bristol University, Upper Maudlin Street, Bristol, BS2 8HW UK.
Jeremy ChanBristol Heart Institute, Bristol Royal Infirmary, Bristol University, Upper Maudlin Street, Bristol, BS2 8HW UK.
Tim DongBristol Heart Institute, Bristol Royal Infirmary, Bristol University, Upper Maudlin Street, Bristol, BS2 8HW UK.
Charles TanBristol Heart Institute, Bristol Royal Infirmary, Bristol University, Upper Maudlin Street, Bristol, BS2 8HW UK.
Tugba AydinBristol Heart Institute, Bristol Royal Infirmary, Bristol University, Upper Maudlin Street, Bristol, BS2 8HW UK.
Daniel Paul FuduluBristol Heart Institute, Bristol Royal Infirmary, Bristol University, Upper Maudlin Street, Bristol, BS2 8HW UK.
Gianni Davide AngeliniBristol Heart Institute, Bristol Royal Infirmary, Bristol University, Upper Maudlin Street, Bristol, BS2 8HW UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Over the past two decades, early mortality following re-operative aortic valve surgery has declined significantly; however, it remains higher than that observed after primary isolated valve replacement. We sought to examine temporal trends and identify independent predictors of adverse outcomes in patients undergoing re-operative aortic valve surgery. Method: The study included all patients undergoing re-operative aortic valve replacement (AVR) in the United Kingdom between January-1996 and March-2019 including those with multiple previous operations and those undergoing additional procedures. Data was obtained from the National Institute of Cardiovascular Outcomes Research database. The primary objective was to assess in-hospital mortality trends. Secondary objective was to identify risk factors for in-hospital mortality. Multivariable analysis was carried out to identify independent risk factors for in-hospital mortality. Results: During the study period, 6,109 re-operative aortic valve surgeries were carried out in the United Kingdom. There were 1,973(32%) females, median age was 69(60-76) years with median duration between the initial and the reoperation being 7(2-13) years. Bio-prosthetic valves were more commonly explanted compared to mechanical valves: 4,125(68%) vs. 1,641(27%). Mortality for elective re-operative cases was 4.8% ( Conclusion: With advances in management strategies, mortality following re-operative AVR continues to decline, but still remains significant. Structural degeneration of bioprosthetic valves continues to be the most common indication for re-operation Emergency re-operations are associated with substantially higher mortality rates; therefore, close follow-up of these patients is essential to facilitate timely elective re-intervention before clinical deterioration. Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s12055-025-01980-1.

Indexed as

Aortic valve replacementRedo aortic valve surgeryRe-operative surgery

Identifiers

PMID40860399
PMCPMC12373612

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.