Evidence map›Paper›PMID 40860383›Full record

ArticleJournal of conservative dentistry and endodontics2025

Comparative antimicrobial efficacy of triple antibiotic paste, 2% chlorhexidine gel, and bromelain paste against

Shrunkhal Dilip Bhupal, Surbhi Pawan Patel, Meenal Nitin Gulve, Swapnil J Kolhe, Priyanka Swapnil Kolhe, Pawan A Pawar

Abstract read
In one paragraph

Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Evaluation of antimicrobial efficacy of two commercially available probiotics againstJournal of conservative dentistry and endodontics · 2026
    Article
  2. Antibacterial efficacy of calcium hydroxide, polyantibiotic paste, andJournal of conservative dentistry and endodontics · 2026
    Article
  3. Article
  4. AnJournal of conservative dentistry and endodontics · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shrunkhal Dilip BhupalDepartment of Conservative Dentistry and Endodontics, MGV's Karmaveer Bhausaheb Hiray Dental College and Hospital, Nashik, Maharashtra, India.
Surbhi Pawan PatelDepartment of Conservative Dentistry and Endodontics, MGV's Karmaveer Bhausaheb Hiray Dental College and Hospital, Nashik, Maharashtra, India.
Meenal Nitin GulveDepartment of Conservative Dentistry and Endodontics, MGV's Karmaveer Bhausaheb Hiray Dental College and Hospital, Nashik, Maharashtra, India.
Swapnil J KolheDepartment of Conservative Dentistry and Endodontics, MGV's Karmaveer Bhausaheb Hiray Dental College and Hospital, Nashik, Maharashtra, India.
Priyanka Swapnil KolheDepartment of Conservative Dentistry and Endodontics, MGV's Karmaveer Bhausaheb Hiray Dental College and Hospital, Nashik, Maharashtra, India.
Pawan A PawarDepartment of Conservative Dentistry and Endodontics, MGV's Karmaveer Bhausaheb Hiray Dental College and Hospital, Nashik, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Given the need to balance safety and effectiveness issues with synthetic agents, herbal alternatives may offer advantages when employed as intracanal medicaments (ICMs). Aim: This randomized control trial assessed antimicrobial efficacy of triple antibiotic paste (TAP), 2% chlorhexidine (CHX) gel, and Bromelain paste as ICM against Settings and Design: This is randomized controlled clinical trial. Subjects and Methods: Twenty-four patients with nonvital teeth and single root canals were selected. Following initial access opening and biomechanical preparation, first microbial samples (S1) were collected using paper points. Patients were divided into three groups ( Statistical Analysis Used: The comparison of difference in CFU count among three groups was performed using the one-way ANOVA test ( Results: Reduction in CFU count postmedication S2 (S2a, S2b, and S2c) from S1 in each group was statistically significant. Reduction in CFU count was the highest in Group 3 (S2c) (Bromelain) (3.11 × 10 Conclusions: Bromelain showed the greatest reduction in

Indexed as

Bromelain pastechlorhexidine gelcolony-forming unitsEnterococcus faecalistriple antibiotic paste

Identifiers

PMID40860383
PMCPMC12377671

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.