Evidence map›Paper›PMID 40860354›Full record

ReviewFrontiers in cardiovascular medicine2025

Brugada syndrome in the forensic field: what do we know to date?

Oscar Campuzano, Simone Grassi, Estefanía Martínez-Barrios, Andrea Greco, Vincenzo Arena, Georgia Sarquella-Brugada, Antonio Oliva

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Oscar Campuzano *Medical Science Department, School of Medicine, University of Girona, Girona, Spain.
Simone Grassi *Department of Health Sciences, Section of Forensic Medical Sciences, University of Florence, Florence, Italy.
Estefanía Martínez-BarriosPediatric Arrhythmias, Inherited Cardiac Diseases and Sudden Death Unit, Cardiology Department, Sant Joan de Déu Hospital de Barcelona, Barcelona, Spain.
Andrea GrecoPediatric Arrhythmias, Inherited Cardiac Diseases and Sudden Death Unit, Cardiology Department, Sant Joan de Déu Hospital de Barcelona, Barcelona, Spain.
Vincenzo ArenaArea of Pathology, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Georgia Sarquella-BrugadaMedical Science Department, School of Medicine, University of Girona, Girona, Spain.
Antonio OlivaInstitute of Public Health, Section Legal Medicine, Catholic University, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brugada Syndrome is a cardiac genetic entity associated with an elevated risk of life-threatening arrhythmias, making accurate and prompt diagnosis vital to prevent lethal outcomes. To date, no macroscopic alterations have been identified in diagnosed patients, but microscopic alterations have been reported in some cases, which remain a matter of argue. This is especially relevant in the forensic field, helping to perform a post-mortem diagnose. Molecular autopsy may help to identify the genetic alteration, but other data such as family history and the situation of death are crucial to unravel the definite cause of an unexpected decease. Deleterious variants in the

Indexed as

Brugada syndromechannelopathiesforensicsmolecular autopsystructural alterationssudden cardiac death

Identifiers

PMID40860354
PMCPMC12375665

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.