Evidence map›Paper›PMID 40860235›Full record

ArticleTetrahedron letters2025

Halogenated Pyridine Derivatives from Cycloaddition / Cycloreversion of Oxazinone and Haloalkyne Precursors.

Elizabeth A Davis, Megan S Hammett, Jonathan R Scheerer

Abstract read
In one paragraph

Article in Tetrahedron letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth A DavisDepartment of Chemistry, William & Mary, P.O. Box 8795, Williamsburg, Virginia 23187, United States.
Megan S HammettDepartment of Chemistry, William & Mary, P.O. Box 8795, Williamsburg, Virginia 23187, United States.
Jonathan R ScheererDepartment of Chemistry, William & Mary, P.O. Box 8795, Williamsburg, Virginia 23187, United States.ORCID 0000-0003-3283-0220

Funding

New methods to prepare 1,4-oxazin-2-ones and applications in the construction of polysubstituted pyridinesR15GM107702 · NIGMS · COLLEGE OF WILLIAM AND MARY · PI SCHEERER, JONATHAN R · 2014 to 2023
$987k
NIGMS NIH HHS R15 GM107702
6 · The paper itself

Abstract

This study explores the merged cycloaddition/cycloreversion of 1,4-oxazinone substrates with haloalkyne 2π reaction components. Haloalkynes proved generally competent in the Diels-Alder operation and exerted a small influence on the regioselection of the reaction sequence as compared to the reaction sequence with the derived terminal alkyne precursors. Following tandem cycloreversion and elimination of CO

Indexed as

1,4-oxazinonecycloadditioncycloreversionDiels-Alderheterocyclespyridine

Identifiers

PMID40860235
PMCPMC12373122

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.