Evidence map›Paper›PMID 40860187›Full record

ArticleInternational journal of biological sciences2025

Activation of sphingosine-1-phosphate receptors can relieve myocardial ischemia-reperfusion injury by mitigating oxidative stress and ferroptosis in cardiomyocytes.

Xuan Xu, Runqian Li, Shengnan Li, Qin Wei, Fuchao Yu, Genshan Ma, Jiayi Tong

Abstract read
In one paragraph

Article in International journal of biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuan XuDepartment of Cardiology, Zhongda Hospital, Southeast University, 87 Dingjiaqiao, Nanjing 210009, P.R. China.
Runqian LiSchool of medicine, Southeast University, Nanjing 210009, P. R. China.
Shengnan LiSchool of medicine, Southeast University, Nanjing 210009, P. R. China.
Qin WeiDepartment of Cardiology, Zhongda Hospital, Southeast University, 87 Dingjiaqiao, Nanjing 210009, P.R. China.
Fuchao YuDepartment of Cardiology, Zhongda Hospital, Southeast University, 87 Dingjiaqiao, Nanjing 210009, P.R. China.
Genshan MaDepartment of Cardiology, Zhongda Hospital, Southeast University, 87 Dingjiaqiao, Nanjing 210009, P.R. China.
Jiayi TongDepartment of Cardiology, Zhongda Hospital, Southeast University, 87 Dingjiaqiao, Nanjing 210009, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

FerroptosisMyocardial Reperfusion InjuryMyocytes, CardiacOxidative StressReceptors, LysosphingolipidSphingosine-1-Phosphate ReceptorsAnimalsMaleMiceMice, Inbred C57BLReactive Oxygen SpeciesSignal TransductionSTAT3 Transcription FactorReactive Oxygen SpeciesReceptors, LysosphingolipidSphingosine-1-Phosphate ReceptorsSTAT3 Transcription Factorferroptosismyocardial ischemiareactive oxygen speciesreperfusion injurysphingosine-1-phosphate receptors

Identifiers

PMID40860187
PMCPMC12374838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.