Evidence map›Paper›PMID 40860184›Full record

ArticleInternational journal of biological sciences2025

Blocking interplay between TERT and c-Myc: a new therapeutic strategy for

Jing Wei, Jiazhe Liu, Yan Zhang, Guobin Wang, Xiao Cui, Wei Yu, Chunlei Nie, Peng Hou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Preoperative Co-Mutation of BRAFCancer medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing WeiDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.
Jiazhe LiuDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.
Yan ZhangDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.
Guobin WangDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.
Xiao CuiDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.
Wei YuDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.
Chunlei NieDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin 163711, P.R. China.
Peng HouDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumors with coexisting mutations of

Indexed as

Proto-Oncogene Proteins B-rafProto-Oncogene Proteins c-mycTelomeraseAnimalsCell Line, TumorGene Expression Regulation, NeoplasticHumansMiceMice, NudeMutationPromoter Regions, GeneticBRAF protein, humanMYC protein, humanProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-mycTelomeraseTERT protein, humanBRAFV600E mutationc-Myc stabilityPeptide-gold nanoparticlespTERT mutations

Identifiers

PMID40860184
PMCPMC12374824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.