Evidence map›Paper›PMID 40860180›Full record

ArticleInternational journal of biological sciences2025

Citrus Pectin Supplementation Alleviated Hepatic Lipid Accumulation through Gut Microbiota Indole Lactic Acid Promoting Hepatic Bile Acid Synthesis and Excretion.

Zhijun Pan, Xinyuan Jin, Qing Li, Yuqing Zhou, Yupeng Zeng, Xin Wang, Yufeng Jin, Yu Chen, Dan Li, Wenhua Ling

Abstract read
In one paragraph

Article in International journal of biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Soluble Dietary Fiber fromInternational journal of molecular sciences · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhijun PanDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Xinyuan JinDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Qing LiDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Yuqing ZhouDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Yupeng ZengDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Xin WangDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Yufeng JinDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Yu ChenDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Dan LiDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.
Wenhua LingDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China, 510080.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic-associated fatty liver disease (MAFLD) represents a critical global health challenge. A few studies have suggested that citrus pectin may confer protective effects against MAFLD; however, the underlying mechanism remains unclear. The gut microbiota and its metabolites strongly contribute to MAFLD regulation by the gut‒liver axis. The present study explored the influence of pectin intervention on liver lipid accumulation in high-fat and high-sugar diet-fed mouse models. Pectin supplementation alleviated hepatic lipid accumulation and substantially restructured the gut microbial communities, particularly enhancing the proliferation of

Indexed as

Bile Acids and SaltsGastrointestinal MicrobiomeIndolesLipid MetabolismLiverPectinsAnimalsDietary SupplementsDiet, High-FatMaleMiceMice, Inbred C57BLBile Acids and Saltscitrus pectinIndolesPectinscitrus pectingut microbiotahepatic lipid accumulationIndole-3-lactic acid

Identifiers

PMID40860180
PMCPMC12374830

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.