Evidence map›Paper›PMID 40860176›Full record

ArticleStigma and health2025

The Acute Inflammatory Effects of Weight Stigma: An Experimental Pilot Study.

Natalie G Keirns, Bryant H Keirns, Cindy E Tsotsoros, Harley M Layman, Madison E Stout, Christina M Sciarrillo, Sam R Emerson, Jennifer Byrd-Craven, Jaimie Arona Krems, Rebecca L Pearl and 2 more

Abstract read
In one paragraph

Article in Stigma and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Experienced Weight Stigma Changes Following Bariatric Surgery: a Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Article
  3. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Natalie G KeirnsDivision of Cardiology, The Miriam Hospital, Lifespan.
Bryant H KeirnsDepartment of Nutrition and Health Science, Ball State University.
Cindy E TsotsorosDepartment of Human Development and Family Science, University of Rhode Island.
Harley M LaymanDepartment of Psychology, Oklahoma State University.
Madison E StoutDepartment of Psychology, Oklahoma State University.
Christina M SciarrilloDepartment of Nutritional Sciences, Oklahoma State University.
Sam R EmersonDepartment of Nutritional Sciences, Oklahoma State University.
Jennifer Byrd-CravenDepartment of Psychology, Oklahoma State University.
Jaimie Arona KremsDepartment of Psychology, University of California, Los Angeles.
Rebecca L PearlDepartment of Clinical and Health Psychology, University of Florida.
A Janet TomiyamaDepartment of Psychology, University of California, Los Angeles.
Misty A W HawkinsDepartment of Health & Wellness Design, Indiana University, Bloomington.

Funding

The Impact of Maternal Adversity and Attachment Security on Infant Stress Reactivity: Prenatal Epigenetic PathwaysP20GM109097 · NIGMS · OSU CENTER FOR HEALTH SCIENCES · PI Jason A. Avery · 2016 to 2026
$22.8M
Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Reducing Weight Stigma to Improve Long-Term Weight LossK23HL140176 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PEARL, REBECCA L · 2018 to 2022
$835k
Acute Inflammatory Effects of Weight Stigma in Overweight/ObesityF31HL152620 · NHLBI · OKLAHOMA STATE UNIVERSITY STILLWATER · PI KEIRNS, NATALIE · 2020 to 2021
$62k
NHLBI NIH HHS F31 HL152620NHLBI NIH HHS K23 HL140176NIDDK NIH HHS P30 DK097512NIGMS NIH HHS P20 GM109097
6 · The paper itself

Abstract

Weight stigma is a chronic stressor and may contribute to cardiometabolic health risk. This pilot study tests an experimental protocol exploring acute inflammation as a potential biological mechanism connecting weight stigma and disease risk. Preliminary effect sizes and protocol feasibility were assessed. Women (

Indexed as

Cardiometabolic DiseaseInflammationStressWeight Stigma

Identifiers

PMID40860176
PMCPMC12372991

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.