Evidence map›Paper›PMID 40860154›Full record

ArticleTheranostics2025

An unrecognized mechanism of self-protection in degenerating neurons mediated by astrocytic YAP through Wnts/β-catenin/EAAT2 signaling in C9orf72-poly-GA mice.

Dongmei Li, Yan Wei, Rui Yang, Xuan Luo, Yanzhu Liu, Weiqiao Zhao, Hui Yang, Yumin Wu, Ying Wang, Zhihui Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dongmei LiSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Yan WeiSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Rui YangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Xuan LuoSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Yanzhu LiuSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Weiqiao ZhaoSchool of Basic Medicine, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Hui YangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.
Yumin WuDepartment of Orthopedics (Spine Surgery), the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China.
Ying WangDepartment of Clinical Research Center, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou 310006, Zhejiang, China.
Zhihui HuangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptor Proteins, Signal TransducingAmyotrophic Lateral SclerosisAstrocytesC9orf72 ProteinCell Cycle ProteinsExcitatory Amino Acid Transporter 2Wnt Signaling PathwayAnimalsbeta CateninDisease Models, AnimalHumansMiceMice, KnockoutMotor NeuronsNeuronsSignal TransductionAdaptor Proteins, Signal Transducingbeta CateninC9orf72 ProteinC9orf72 protein, mouseCell Cycle ProteinsExcitatory Amino Acid Transporter 2Slc1a2 protein, mouseYap1 protein, mouseYAP-Signaling ProteinsALSEAAT2motor dysfunctionneurodegenerationYAP

Identifiers

PMID40860154
PMCPMC12374586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.