Fungal laccase-guided copper nanoflower assembly enables complete conversion of HMF to FDCA.

Lei Yang, Anbang Duan, Yuan Ding, Xiquan Song, Qianli Ma, Zhanyin Liu, Tingying Wei, Zhixing Wang, Chunzhao Liu

Abstract read

In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

9 authors.

Lei YangState Key Laboratory of Bio-fibers and Eco-Textiles, Institute of Biochemical Engineering, The 3rd Clinical College of Qingdao University, College of Materials Science and Engineering, Qingdao University Qingdao 266071 China wangzhixing@qdu.edu.cn czliu@qdu.edu.cn.ORCID https://orcid.org/0009-0003-5917-0215

Anbang DuanState Key Laboratory of Bio-fibers and Eco-Textiles, Institute of Biochemical Engineering, The 3rd Clinical College of Qingdao University, College of Materials Science and Engineering, Qingdao University Qingdao 266071 China wangzhixing@qdu.edu.cn czliu@qdu.edu.cn.

Yuan DingState Key Laboratory of Bio-fibers and Eco-Textiles, Institute of Biochemical Engineering, The 3rd Clinical College of Qingdao University, College of Materials Science and Engineering, Qingdao University Qingdao 266071 China wangzhixing@qdu.edu.cn czliu@qdu.edu.cn.

Xiquan SongTayho Advanced Materials Group Co. Ltd. Yantai 264006 China.

Qianli MaTayho Advanced Materials Group Co. Ltd. Yantai 264006 China.

Zhanyin LiuState Key Laboratory of Bio-fibers and Eco-Textiles, Institute of Biochemical Engineering, The 3rd Clinical College of Qingdao University, College of Materials Science and Engineering, Qingdao University Qingdao 266071 China wangzhixing@qdu.edu.cn czliu@qdu.edu.cn.

Tingying WeiState Key Laboratory of Bio-fibers and Eco-Textiles, Institute of Biochemical Engineering, The 3rd Clinical College of Qingdao University, College of Materials Science and Engineering, Qingdao University Qingdao 266071 China wangzhixing@qdu.edu.cn czliu@qdu.edu.cn.

Zhixing WangState Key Laboratory of Bio-fibers and Eco-Textiles, Institute of Biochemical Engineering, The 3rd Clinical College of Qingdao University, College of Materials Science and Engineering, Qingdao University Qingdao 266071 China wangzhixing@qdu.edu.cn czliu@qdu.edu.cn.

Chunzhao LiuState Key Laboratory of Bio-fibers and Eco-Textiles, Institute of Biochemical Engineering, The 3rd Clinical College of Qingdao University, College of Materials Science and Engineering, Qingdao University Qingdao 266071 China wangzhixing@qdu.edu.cn czliu@qdu.edu.cn.ORCID https://orcid.org/0000-0003-4432-0703

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing demand for sustainable biomanufacturing has driven significant interest in 2,5-furandicarboxylic acid (FDCA), a bio-based platform chemical for producing renewable polymers. The eco-friendly oxidoreductase laccase exhibits promising FDCA biosynthesis capacity yet is hampered by pH-dependent activity decay and susceptibility to proteolytic degradation. Herein, we developed a bio-enabled synthesis approach to fabricate three-dimensional laccase-integrated copper hybrid nanoflowers (Lac-NFs) through enzyme-metal coordination-driven self-assembly. The engineered Lac-NFs displayed high enzyme encapsulation efficiency (89.28%) and enhanced environmental robustness compared to free laccase. Furthermore, the Lac-NFs maintained prolonged storage stability with well-preserved activity relative to the native enzyme. Elevated catalytic efficiency and refined enzymatic kinetics were achieved

Identifiers

PMID40860086

DOI10.1039/d5ra04187b

PMCPMC12376868

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LicenceCC BY-NC

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.