Evidence map›Paper›PMID 40860021›Full record

ArticleHRB open research2025

Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol.

Bethany Cushing, Benjamin Jacob, XinYi Low, Sam McGlynn, Ildiko Horvath, Martina Vranka, Tytti Sarkeala, Patrick Redmond

Abstract read
In one paragraph

Article in HRB open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bethany CushingRoyal College of Surgeons in Ireland School of Medicine, Dublin, Leinster, Ireland.ORCID https://orcid.org/0009-0003-1896-5732
Benjamin JacobRoyal College of Surgeons in Ireland Department of General Practice, Dublin, Leinster, Ireland.ORCID https://orcid.org/0000-0003-1119-064X
XinYi LowRoyal College of Surgeons in Ireland School of Medicine, Dublin, Leinster, Ireland.ORCID https://orcid.org/0009-0006-7987-4967
Sam McGlynnRoyal College of Surgeons in Ireland Department of General Practice, Dublin, Leinster, Ireland.
Ildiko HorvathNational Koranyi Institute for Pulmonology, Budapest, Hungary.
Martina VrankaDivision of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia.
Tytti SarkealaFinnish Cancer Registry, Helsinki, 00500, Finland.
Patrick RedmondRoyal College of Surgeons in Ireland Department of General Practice, Dublin, Leinster, Ireland.ORCID https://orcid.org/0000-0002-3929-2018

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lung cancer is the leading cause of cancer-related mortality worldwide. Low-dose CT (LDCT) lung cancer screening (LCS) reduces lung cancer-specific mortality by 20%, yet participation remains low, often below 15%, compared with 60-75% for other cancer screening programmes. Barriers such as limited accessibility, stigma, fear of diagnosis, and misconceptions contribute to poor uptake, particularly among high-risk groups, including heavy smokers, ethnic minorities, and individuals from lower socioeconomic backgrounds. Various recruitment strategies-such as personalised invitations, media campaigns, and primary care referrals-have been implemented, but their effectiveness across different populations remains unclear. This umbrella review will synthesise evidence from systematic reviews to identify the most effective recruitment strategies for improving LCS participation. Methods: This umbrella review will follow Joanna Briggs Institute guidelines and the PRIOR reporting framework. A systematic search of PubMed, Embase, Scopus, Web of Science, Cochrane Library, and systematic review registries will identify systematic reviews published before 31 October 2024. Eligible reviews must evaluate LCS recruitment strategies and report on at least one of the following: population reach, screening up take, adherence, patient experience, or implementation barriers. Quality will be assessed using AMSTAR 2, and overlapping primary studies will be mapped to prevent duplication. A narrative synthesis will categorise recruitment strategies, and a qualitative effectiveness ranking will summarise key findings. Implications: Findings will inform LCS recruitment strategies in Europe, contributing to the EU4Health-funded EUCanScreen programme. This review will support efforts to improve uptake, reduce disparities, and enhance early detection and survival outcomes of lung cancer.

Indexed as

Umbrella review; Early detection of cancer; Cancer screening; Lung cancer; participation; Primary care

Identifiers

PMID40860021
PMCPMC12375178

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.