Evidence map›Paper›PMID 40859978›Full record

ArticleDrug design, development and therapy2025

Design, Synthesis and Anti-Inflammation Evaluation of

Bingqian Han, Shiyu Ma, Wenjin Liu, Yuyang Wang, Mingzhu Wang, Yuanzhe Li, Chuanjun Song, Yongfang Yao, Moran Sun, Yongtao Duan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug design, development and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bingqian Han *Henan Provincial Key Laboratory of Pediatric Hematology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Shiyu Ma *College of Chemistry, Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Wenjin Liu *School of Pharmaceutical Science, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yuyang Wang *School of Pharmaceutical Science, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Mingzhu WangHenan Provincial Key Laboratory of Pediatric Hematology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yuanzhe LiHenan Provincial Key Laboratory of Pediatric Hematology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Chuanjun SongCollege of Chemistry, Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yongfang YaoHenan Provincial Key Laboratory of Pediatric Hematology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Moran SunSchool of Pharmaceutical Science, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yongtao DuanHenan Provincial Key Laboratory of Pediatric Hematology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The P2Y Methods: Three series of novel P2Y Results: We designed a series of Conclusion: Compound

Indexed as

Acute Lung InjuryAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalDrug DesignPurinergic P2 Receptor AntagonistsTryptophanAnimalsDisease Models, AnimalDose-Response Relationship, DrugHumansLipopolysaccharidesMaleMiceMice, Inbred C57BLMolecular StructureReceptors, Purinergic P2Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalLipopolysaccharidesP2Y14 receptor, humanPurinergic P2 Receptor AntagonistsReceptors, Purinergic P2Tryptophanantagonistanti-inflammatory activityG protein-coupled receptorN-acyl tryptophan derivativesP2Y14 receptor

Identifiers

PMID40859978
PMCPMC12375329

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.