Evidence map›Paper›PMID 40859955›Full record

ArticleMedComm2025

Activated Interferon-γ-Positive T Lymphocytes and Cytokine Signatures in Patients With Postinfectious Cough.

Zheng Deng, Tongtong Song, Wenbin Ding, Wei Luo, Jiaxing Xie, Haodong Wu, Nanshan Zhong, Kefang Lai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zheng DengState Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.ORCID https://orcid.org/0000-0002-2203-6384
Tongtong SongState Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Wenbin DingState Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Wei LuoState Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Jiaxing XieState Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Haodong WuState Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Nanshan ZhongState Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Kefang LaiState Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postinfectious subacute cough (PISC) and postinfectious chronic cough (PICC) are triggered by respiratory infections, which induce adaptive immunity. The expression of T-lymphocyte subsets and cytokine signatures remains elusive in these patients. Here, we recruited 40 healthy controls, 64 PICC patients, 65 PISC patients, and 20 recovered individuals with postinfectious subacute cough (R-PISC). As cough and airway inflammation resolved in R-PISC subjects, sputum lymphocytes dropped substantially. Both PICC and PISC patients had an increase in blood activated interferon-γ (IFN-γ)

Indexed as

airway inflammationcytokinesimmune responsespostinfectious coughT lymphocytes

Identifiers

PMID40859955
PMCPMC12375690

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.