Evidence map›Paper›PMID 40859876›Full record

ArticleContact dermatitis2025

Evaluation of Artificial Intelligence-Assisted Diagnosis of Skin Erythema in a Patch Test.

Seoyoung Kim, Hyunsik Hwang, Mihyun Oh, Jieun Han, Sodam Park, Soyoung Lee, Goun Kim, Sungwon Cho, Dong Hun Lee, Jae Youl Cho

Abstract read
In one paragraph

Article in Contact dermatitis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seoyoung KimSafety and Microbiology Lab, AMOREPACIFIC R&I Center, Gyeonggi-do, South Korea.ORCID https://orcid.org/0000-0001-7685-2654
Hyunsik HwangImagineFactory, Seoul, South Korea.
Mihyun OhSafety and Microbiology Lab, AMOREPACIFIC R&I Center, Gyeonggi-do, South Korea.
Jieun HanSafety and Microbiology Lab, AMOREPACIFIC R&I Center, Gyeonggi-do, South Korea.
Sodam ParkSafety and Microbiology Lab, AMOREPACIFIC R&I Center, Gyeonggi-do, South Korea.
Soyoung LeeSafety and Microbiology Lab, AMOREPACIFIC R&I Center, Gyeonggi-do, South Korea.
Goun KimSafety and Microbiology Lab, AMOREPACIFIC R&I Center, Gyeonggi-do, South Korea.
Sungwon ChoImagineFactory, Seoul, South Korea.
Dong Hun LeeDepartment of Dermatology, Seoul National University College of Medicine, Seoul, South Korea.
Jae Youl ChoDepartment of Integrative Biotechnology, Sungkyunkwan University, Suwon, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe patch test evaluates skin erythema, infiltration, papules and vesicles following exposure to various substances, including metals, cosmetics and medicines. Accurate evaluation of these conditions requires consistent skin score assessments, precise visual grading and minimal inter-expert variability.

objectivesThis study aimed to develop a skin irritation artificial intelligence model based on the YOLOv5x object detection framework to automatically detect skin irritation from the patch test images for multiple test substances.

methodsPatch test images were collected with test sites marked to enable the YOLOv5x algorithm to locate the samples. An expert assigned a score to each sample (0-4) for training and validation. The model was trained using 83 629 data points. Evaluation and validation were performed with 1312 and 1536 data points, respectively.

resultsThe model achieved an overall accuracy of 0.983 at both 24 and 48 h, with an F1 score (harmonic mean of recall and precision) of 0.982. The areas under the curve (AUCs) for scores 0, 1 and 2 were 0.914, 0.838 and 0.865, respectively. The sensitivity for a score of 0 was 0.997.

conclusionThese findings suggest that this AI model effectively supports and classifies skin irritation, thereby facilitating faster and more accurate dermatological evaluations.

Indexed as

Artificial IntelligenceDermatitis, Allergic ContactDiagnosis, Computer-AssistedErythemaPatch TestsAlgorithmsHumansAIhuman patch testskin irritationYOLOv5x

Identifiers

PMID40859876
PMCPMC12503976

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.