Evidence map›Paper›PMID 40859864›Full record

ArticleAddiction biology2025

Neural Correlates of Resistance to Gaming Desire Induced by Social Media Content.

Yuka Fujimoto, Junya Fujino, Daisuke Matsuyoshi, Daisuke Jitoku, Nanase Kobayashi, Chenyu Qian, Shoko Okuzumi, Shisei Tei, Takehiro Tamura, Takefumi Ueno and 2 more

Abstract read
In one paragraph

Article in Addiction biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuka FujimotoDepartment of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Junya FujinoDepartment of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.ORCID 0000-0001-7716-2401
Daisuke MatsuyoshiInstitute for Quantum Life Science, National Institutes for Quantum Science and Technology, Chiba, Japan.
Daisuke JitokuDepartment of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Nanase KobayashiDepartment of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Chenyu QianDepartment of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Shoko OkuzumiDepartment of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Shisei TeiMedical Institute of Developmental Disabilities Research, Showa University, Tokyo, Japan.
Takehiro TamuraDepartment of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Takefumi UenoDivision of Clinical Research, National Hospital Organization, Hizen Psychiatric Medical Center, Saga, Japan.
Makiko YamadaInstitute for Quantum Life Science, National Institutes for Quantum Science and Technology, Chiba, Japan.
Hidehiko TakahashiDepartment of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.

Funding

CREST JPMJCR22P3Intramural Research Grant (4-1) for Neurological and Psychiatric Disorders of NCNPJapan Agency for Medical Research and Development JP23dk0307102Japan Agency for Medical Research and Development JP24dk0307128Japan Science and Technology AgencyJST Moonshot R&D Grant JPMJMS2295-01KAKENHI JP 23H04979KAKENHI JP 23K06981KAKENHI JP 25K10811KDDI Corporation (KDDI Research Inc)Ministry of Education, Culture, Sports, Science and Technology of Japan
6 · The paper itself

Abstract

The rise of gaming-related content on social media has increased exposure to game-related stimuli, particularly among young people, which may reinforce gaming urges and create difficulties in controlling gaming behaviour. Therefore, understanding the management of gaming desire triggered by such content is critical. Identifying the neural mechanisms underlying resistance to these urges will be crucial for effective prevention and intervention. However, this issue has yet to be directly explored. The present study investigated the neural correlates of resisting gaming desire elicited by gaming-related social media videos using functional magnetic resonance imaging (fMRI). Young habitual online gamers participated in an fMRI study in which they viewed video stimuli under three conditions: (1) gaming cue condition: passive viewing of gaming-related videos; (2) gaming cue resist condition: viewing of gaming-related videos while actively resisting gaming desire; and (3) neutral cue condition. Gaming cues elicited significantly greater activation than neutral cues in the diverse brain areas including bilateral medial prefrontal cortex, orbitofrontal cortex, anterior cingulate cortex, posterior cingulate cortex (PCC), superior temporal gyrus (STG) and precuneus. Compared to the gaming cue condition, the gaming cue resist condition elicited increased activation in the left PCC and bilateral precuneus. Conversely, significant deactivation was observed in the right STG. These findings offer insights into the neural basis of craving resistance in response to social media-based gaming cues and may guide the development of targeted interventions for problematic gaming behaviour.

Indexed as

BrainCravingInternet Addiction DisorderSocial MediaVideo GamesAdolescentAdultBrain MappingCuesFemaleGyrus CinguliHumansMagnetic Resonance ImagingMalePrefrontal CortexYoung Adultcravingfunctional magnetic resonance imaginggaming addictionposterior cingulate cortexprecuneus

Identifiers

PMID40859864
PMCPMC12381575

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.