Evidence map›Paper›PMID 40859830›Full record

ArticleCirculation. Heart failure2025

Myosin Mayhem: Losing (or Gaining) Its Chill in Hypertrophic Cardiomyopathy.

Brett A Colson

Abstract readEditorialComment
In one paragraph

Article in Circulation. Heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Brett A ColsonDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson.ORCID 0000-0002-5721-4320

Funding

PHYSIOLOGYT32HL007249 · NHLBI · UNIVERSITY OF ARIZONA · PI Brett A Colson, JOHN P KONHILAS · 1985 to 2026
$12.5M
Structural Dynamics of Cardiac Myosin-Binding Protein C RegulationR01HL141564 · NHLBI · UNIVERSITY OF ARIZONA · PI Brett A Colson · 2019 to 2026
$3.8M
Skeletal Myosin-Binding Protein C Regulation and Structural DynamicsR01AR079435 · NIAMS · UNIVERSITY OF ARIZONA · PI Brett A Colson · 2022 to 2026
$2.4M
NHLBI NIH HHS R01 HL141564NHLBI NIH HHS T32 HL007249NIAMS NIH HHS R01 AR079435
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiomyopathiesEditorials ◼ actinsgenotypemotivationmyocardiummyosins

Identifiers

PMID40859830
PMCPMC12606676

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.