SynthesisJournal of health, population, and nutrition2025
Global prevalence of dyslipidemias in the general adult population: a systematic review and meta-analysis.
Synthesis in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07695376 (CArdiovascular Risk Assessment Via Multimodal Data Analysis Enabling Personalised Prevention Strategies Targeting MEnopausaL Women - Observational Study), which is not on this map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
CArdiovascular Risk Assessment Via Multimodal Data Analysis Enabling Personalised Prevention Strategies Targeting MEnopausaL Women - Observational Study
Who cites it
32 citing papers in PubMed.
- Lower 24-hour urinary 6-sulfatoxymelatonin and exploratory bile-acid and microbiome associations in adults with dyslipidemia: a prospectively enrolled cross-sectional study.Annals of medicine · 2026Article
- Treat-to-target strategies for low-density lipoprotein cholesterol and triglyceride levels for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia.The Cochrane database of systematic reviews · 2026Article
- Apolipoprotein E Mimetic Peptide-Mediated Modulation of Lipid Homeostasis.Biomolecules · 2026Review
- Burden of atherosclerotic cardiovascular disease attributable to high body mass index, high fasting plasma glucose or high low density lipoprotein cholesterol in young and middle-aged adults from 1990 to 2050.Diabetology & metabolic syndrome · 2026Article
- Generic Versus Branded Atorvastatin: A Single-Center Comparative Analysis of Clinical Effectiveness and Post-Delisting Cost Savings in Saudi Arabia.Healthcare (Basel, Switzerland) · 2026Article
- Review
- Bempedoic Acid: From Guidelines to the Real World.Journal of lipid and atherosclerosis · 2026Review
- Associations between cardiovascular risk factors and diseases with aortic pulse wave velocity and aortic distensibility: magnetic resonance imaging in the Hamburg city health study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Review
- Associations of Serum Fatty Acids and the Eicosapentaenoic Acid/Arachidonic Acid Ratio with Hypertriglyceridemia in a Japanese Population: A Cross-Sectional Study.Journal of atherosclerosis and thrombosis · 2026Article
- Shared diagnostic biomarkers in metabolic syndrome and coronary artery disease identified by integrated bioinformatics and machine learning.Endocrine connections · 2026Article
- Clustering metabolic and behavioral risk factors for hypertension: evidence from a longitudinal cohort in western Iran.Scientific reports · 2026Article
- Phloretic Acid Improves Metabolic Dysfunction-Associated Steatotic Liver Disease in High-Fat Diet-Fed Mice.Molecules (Basel, Switzerland) · 2026Article
- 4-Hydroxybenzyl Alcohol Mitigates Hyperlipidemia-Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF-κB Pathway.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The association between T4 and TSH with lipid profile is attenuated in patients with established dyslipidemia.BMC endocrine disorders · 2026Article
- Article
- Review
- Physical Activity Modifies the Association between C-Reactive Protein - Triglyceride - Glucose Index (CTI) and Dyslipidemia: Evidence from a 10-Year Chinese Cohort.Journal of sports science & medicine · 2026Article
- Article
- Effects of Walnut Consumption on Blood Lipid Profile and Apolipoproteins in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of 49 Randomized Controlled Trials.Food science & nutrition · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGlobal regional variations in dyslipidemia prevalence underscore the need for an updated global overview of the magnitude of dyslipidemia over time.
objectiveTo estimate the global prevalence of dyslipidemia in adults, considering scientific evidence published in the last 20 years, while analyzing associated sociodemographic and geographic factors. METHODOLOGY: A systematic review and meta-analysis were conducted following PRISMA guidelines. The bibliographic search was performed in PubMed, SCOPUS, Web of Science, and EMBASE, including observational studies published between 2000 and 2025 that reported the prevalence of dyslipidemia components in general adult populations, including hypertriglyceridemia, hypercholesterolemia, hypoalphalipoproteinemia or low high-density lipoprotein cholesterol (HDL-C) levels (< 40 mg/dL for men and < 50 mg/dL for women), and elevated low-density lipoprotein cholesterol (LDL-C). Statistical analyses included meta-analysis with random effects models, stratified analyses by sex and country, and meta-regression by publication year.
resultsA total of 206 studies were included, primarily cross-sectional (98.5%). The global prevalence was 28.8% for hypertriglyceridemia, 24.1% for hypercholesterolemia, 38.4% for low HDL-C, and 18.93% for high LDL-C. Men presented a higher prevalence of hypertriglyceridemia (33.8% vs. 24.5% in women), while women showed a higher frequency of low HDL-C (40.5% vs. 34.1% in men). The highest prevalences of low HDL-C and mixed dyslipidemia patterns were observed in the Middle East and Latin America. Temporal trends revealed a progressive increase in hypertriglyceridemia and low HDL-C, with a decrease in hypercholesterolemia and high LDL-C.
conclusionsThere is an epidemiological transition in the dyslipidemia profile, from classic hypercholesterolemia toward a predominance of hypertriglyceridemia and low HDL-C, with important differences by sex and region. These findings significantly affect cardiovascular prevention and health policies addressing residual risk beyond LDL-C control.
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