SynthesisWorld journal of surgical oncology2025
Application of fluorescent tracers in ovarian cancer surgical navigation: a systematic review and meta-analysis.
Synthesis in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
objectiveOvarian cancer is a lethal gynecological health issue, that poses a serious threat to women's health worldwide. The objective of this study was to provide a literature overview of the application of fluorescent tracers during surgical ovarian cancer treatment.
methodsWe systematically searched 7 electronic databases from inception to September 2024. Studies were included if they investigated the application of fluorescence-guided surgery in patients with a diagnosis of ovarian cancer. Statistical analysis was performed with Stata 14.0 software, and the pooled detection rate and measures of diagnostic accuracy were evaluated. Subgroup analyses were carried out to evaluate the types of tracers, doses, injection sites, etc. Complications and adverse events were also reported. The Quality Assessment of Diagnostic Accuracy Studies 2 tool was used for quality assessment.
resultsA total of 21 studies with 681 participants were included. The overall sentinel lymph node (SLN) detection rate was 86.2% (95% CI: 69.6-97.5%; p = 0.000; I
conclusionFluorescence-guided surgery is a potentially safe and applicable technique in ovarian cancer surgery. However, considering the small number of participants and the heterogeneity, further studies are needed to better evaluate the accuracy outcomes regarding the type of tracer, dose, injection site, etc.
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