ArticleCancer causes & control : CCC2025
Every move matters: physical activity, walking, sedentary behavior, and endometrial cancer survival.
Article in Cancer causes & control : CCC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Post-diagnosis physical activity in relation to mortality among gynecological cancer survivors.Cancer causes & control : CCC · 2026Pooled it
- Intervention mapping to develop a patient-advocate enhanced program to reduce sedentary behavior in endometrial cancer survivors.Journal of cancer survivorship : research and practice · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeExcess body fat increases endometrial cancer risk, and moderate-to-vigorous physical activity (MVPA) lowers risk, but the relationship between post-diagnosis MVPA, walking, sedentary time (SED), and endometrial cancer survival is under-researched.
methodsCancer Prevention Study-II participants self-reported post-diagnosis MVPA (MET hour/week, h/wk), walking (h/wk), and SED (h/wk). Meeting MVPA guidelines was defined as 7.5 to <15 MET h/wk. Walking was categorized as 0, <2, 2-6, or >6 h/wk. SED was divided into tertiles (T1-T3). Hazard ratios and 95% confidence intervals (HR, CI) are calculated using delayed-entry Cox models, adjusted for covariates.
resultsWe identified 1016 endometrial cancer survivors (mean BMI: 27.6, age at diagnosis: 72 years, 97% White, 71% college educated, 93% married). Over an average 13.5 years of follow-up, 511 deaths occurred (232 any cancer, 60 endometrial cancer). Compared to no MVPA, associations were not statistically significant, but point estimates suggest that higher amounts of MVPA [measured on average 1.2-year post-diagnosis] are potentially associated with lower all-cause mortality risk [doubling guidelines (HR: 0.71, 95% CI 0.50, 1.00)] but not total cancer mortality risk. Walking <2 h/wk was associated with higher all-cause mortality risk compared to no walking (HR: 1.45, 95% CI: 1.08, 1.96) but not cancer mortality risk. Limiting SED was not associated with survival.
conclusionThis study suggests that higher amounts of MVPA may be associated with survival among older endometrial cancer survivors; however, further research is needed in larger/pooled cohorts with more cancer deaths.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.