Evidence map›Paper›PMID 40859067›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Intracardiac echocardiography for left ventricular diastolic function assessment during atrial fibrillation ablation.

Jian Liang Tan, Julio Chirinos, Darshak Patel, Dinesh Jagasia, Matthew C Hyman, Gustavo S Guandalini, Saman Nazarian, David Lin, Gregory Supple, David S Frankel and 4 more

Abstract read
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jian Liang TanSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Julio ChirinosDivision of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Darshak PatelSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Dinesh JagasiaDivision of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Matthew C HymanSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Gustavo S GuandaliniSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Saman NazarianSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
David LinSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Gregory SuppleSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
David S FrankelSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
David J CallansSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Francis E MarchlinskiSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jian-Fang RenDivision of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Timothy M MarkmanSection for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Timothy.Markman@pennmedicine.upenn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular (LV) diastolic dysfunction is associated with the development of atrial fibrillation (AF) and risk of recurrence after ablation. The use of an intracardiac echocardiography (ICE) for diastolic function assessment during ablation procedures has not been evaluated.

objectivesTo evaluate the feasibility and utility of ICE obtained measures of LV diastolic function including peak tricuspid regurgitation velocity, trans-mitral flow velocity, mitral annular tissue Doppler velocities, and pulmonary vein flow velocities in patients undergoing AF ablation.

methodsWe conducted a single-center, prospective evaluation of patients undergoing AF ablation between 2022 and 2024. During sinus rhythm, diastolic parameters were measured with the ICE catheter and direct left atrial pressure (LAP) was recorded prior to AF ablation. Elevated LAP was defined as ≥ 12 mmHg. ICE measured diastolic parameters were compared with those measured on transthoracic echocardiography (TTE).

resultsA total of 152 patients (53% male, 69 ± 12 years old, mean CHA

conclusionsICE can be used to assess diastolic function with traditional parameters correlating with both TTE diastolic function and LAP. ICE measures of restrictive filling are associated with the need for post-procedural intravenous diuretics.

Indexed as

Atrial FibrillationCatheter AblationEchocardiographyVentricular Dysfunction, LeftAgedDiastoleFeasibility StudiesFemaleHumansMaleMiddle AgedProspective StudiesAtrial fibrillationDiastolic functionIntracardiac echocardiographyLeft atrial pressureOutcomeTransthoracic echocardiography

Identifiers

PMID40859067
PMCPMC12764652

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.