Observational studyPediatric surgery international2025
Short-interval intravenous indocyanine green administration in pediatric laparoscopic cholecystectomy: a prospective evaluation of visualization and safety.
Observational study in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Pediatric cholecystectomy practices and training: an International Multicenter Survey by the European Union of Medical Specialists (UEMS) Section of Paediatric Surgery.Pediatric surgery international · 2026Article
- Application of indocyanine green fluorescence for hilar bile duct identification and management in laparoscopic hemi-hepatectomy (with video).Surgical endoscopy · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
purposeIndocyanine green (ICG) fluorescence imaging enhances biliary visualization during pediatric laparoscopic cholecystectomy (LC), helping to identify anatomical variants and prevent bile duct injury. Standard pediatric recommendations suggest ICG administration 16-24 h preoperatively; however, this may be impractical. This study aims to evaluate the safety and effectiveness of short-interval ICG administration.
methodsA prospective single-center study (October 2024-June 2025) included pediatric LC patients receiving intravenous Verdye® preoperatively. Visualization of extrahepatic biliary anatomy was assessed intraoperatively using a 5-point Likert scale, HELPFUL (usefulness), and DISTURBED (liver background interference) scores. Data included indication, ICG timing, operative time, and complications according to the Clavien-Dindo classification (C-D).
resultsEleven patients (64% female), median age 14 years (IQR 12,7-15,7) and median weight 65,5 kg (IQR 46,5-80), were included. Five had BMI > 25 kg/m
conclusionShort-interval ICG administration was safe, feasible, and effective in enhancing biliary visualization during pediatric LC. This approach was well-tolerated and provided high-quality imaging without complications.
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