Exploring novel thiazolo[5,4-f]quinoline-based scaffolds as promising antimicrobial agents through synthesis and molecular insights.

Nanees N Soliman, Ahmed A Fadda, Hatem E Gaffer, Nesma M Bayoumy

Abstract read

In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Antibacterial Activity and Cytotoxicity Evaluation of 5-Amino-4-cyano-1,3-oxazole Derivatives: Synthesis, In Silico, and In Vitro Studies.Chemistry & biodiversity · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nanees N SolimanDepartment of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt. naneesnagy@yahoo.com.

Ahmed A FaddaDepartment of Chemistry, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.

Hatem E GafferDepartment of Dyeing, Printing, and Auxiliaries, Textile Institute, National Research Centre, Giza, Cairo, Egypt.

Nesma M BayoumyBasic Science Department, Delta University for Science and Technology, Mansoura, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In pursuit of novel antimicrobial agents, a series of thiazolo[5,4-f]quinoline derivatives incorporating pyridine and thiophene moieties were synthesized and structurally characterized using IR and

Indexed as

Anti-Infective AgentsQuinolinesThiazolesCandida albicansDNA GyraseEscherichia coliMicrobial Sensitivity TestsMolecular Docking SimulationStaphylococcus aureusStructure-Activity RelationshipAnti-Infective AgentsDNA GyraseQuinolinesThiazolesAntimicrobial evaluationDocking studyPyridineQuinolineThiazoleThiophene

Identifiers

PMID40858908

DOI10.1038/s41598-025-16561-w

PMCPMC12381138

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.