Evidence map›Paper›PMID 40858855›Full record

Trial reportScientific reports2025

Palatal donor site management using tissue adhesives with adjunctive coconut oil in a randomized clinical trial.

Melis Yilmaz, Nur Balci, Bestegul Gunay, Hanife Merva Parlak, Ayhan Parmaksiz, Hilal Toygar, H Gencay Keceli

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06583226 (The Effect of Two Different Approaches on Palatal Donor Site Management After De-epithelialized Graft Harvesting), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06583226 nacompletednot on this map

The Effect of Two Different Approaches on Palatal Donor Site Management After De-epithelialized Graft Harvesting: Randomized Clinical Study

TypeinterventionalSponsorMedipol UniversityRan2023 to 2024Enrolled50ConditionsWound HealArmsGelatin sponge stabilization with suture and cyanoacrylate, Gelatin sponge stabilization with suture and cyanoacrylate and coconut oil application
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melis YilmazFaculty of Dentistry, Periodontology Department, Istanbul Medipol University, Istanbul, Turkey.
Nur BalciFaculty of Dentistry, Periodontology Department, Istanbul Medipol University, Istanbul, Turkey. nbalci@medipol.edu.tr.
Bestegul GunayFaculty of Dentistry, Periodontology Department, Istanbul Medipol University, Istanbul, Turkey.
Hanife Merva ParlakFaculty of Dentistry, Periodontology Department, Hacettepe University, Ankara, Turkey.
Ayhan ParmaksizDepartment of Biostatistics, Istanbul Health & Technology University, Istanbul, Turkey.
Hilal ToygarFaculty of Dentistry, Periodontology Department, Istanbul Medipol University, Istanbul, Turkey.
H Gencay KeceliFaculty of Dentistry, Periodontology Department, Hacettepe University, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of the complications occurring in the donor area after epithelialized gingival graft (EGG) harvesting still poses a challenge for clinicians. This study aimed to evaluate the influence of gelatin sponge (GS), cyanoacrylate (CY), and coconut oil (CO) combination in comparison with GS + CY in donor site management. Fifty EGG were harvested from the lateral palate in 50 patients, who were subsequently randomized to receive the GS + CY (control) or GS + CY + CO combination (test). Postoperative pain perception (PP), quantity of analgesics (QA), epithelization level (EL), color match (CM), sensation loss (SL), postoperative discomfort (PD), and delayed bleeding (DB) were evaluated. The GS + CY + CO group showed lower PP scores compared to the GS + CY (p < 0.05). The QA intake was similar in both groups. On day 14, the GS + CY + CO group achieved 80% full EL rate, which was higher than the GS + CY group (32%) (p = 0.002). CM scores were higher in the GS + CY + CO group at all follow-up periods (p < 0.001). Both groups reported similar SL, PD, and DB values (p > 0.05). GS + CY + CO combination is more effective in reducing pain compared to GS + CO in donor site management after EGG harvesting. Additionally, GS + CY + CO combination may accelerate epithelialization and improve color match compared to GS + CY alone.Clinical Trial Registration: ClinicalTrials.gov: NCT06583226.

Indexed as

Coconut OilGingivaPalateTissue AdhesivesTransplant Donor SiteAdultCyanoacrylatesFemaleHumansMaleMiddle AgedPostoperative PainYoung AdultCoconut OilCyanoacrylatesTissue AdhesivesAbsorbable gelatin spongeCoconut oilCyanoacrylatesDonor siteTissue graftsWound healing

Identifiers

PMID40858855
PMCPMC12381217

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.