Evidence map›Paper›PMID 40858662›Full record

ArticleScientific reports2025

Safety and efficacy of very short flow diverters for the treatment of intracranial internal carotid artery aneurysms.

Mohammad-Mahdi Sowlat, Rahim Abo Kasem, Zachary S Hubbard, Hallmon Hughes, Ahmed Muthana, Conor M Cunningham, Julio Isidor, Hidetoshi Matsukawa, Alejandro M Spiotta

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammad-Mahdi Sowlat *Department of Neurosurgery, Medical University of South Carolina, 135 Canon Street, Charleston, SC, 29425, USA.
Rahim Abo Kasem *Department of Neurosurgery, Medical University of South Carolina, 135 Canon Street, Charleston, SC, 29425, USA. rahim.abokasem@louisville.edu.
Zachary S HubbardDepartment of Neurosurgery, Medical University of South Carolina, 135 Canon Street, Charleston, SC, 29425, USA.
Hallmon HughesCollege of Medicine, Medical University of South Carolina, Charleston, SC, USA.
Ahmed MuthanaDepartment of Neurosurgery, University of Baghdad, Baghdad, Iraq.
Conor M CunninghamDepartment of Neurosurgery, Medical University of South Carolina, 135 Canon Street, Charleston, SC, 29425, USA.
Julio IsidorDepartment of Neurosurgery, Medical University of South Carolina, 135 Canon Street, Charleston, SC, 29425, USA.
Hidetoshi MatsukawaDepartment of Neurosurgery, Fukuoka Neurosurgical Hospital, Fukuoka, Japan.
Alejandro M SpiottaDepartment of Neurosurgery, Medical University of South Carolina, 135 Canon Street, Charleston, SC, 29425, USA. spiotta@musc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deploying flow diverters (FDs) around the carotid siphon typically favors longer FDs for easier manipulation and safety, leaving shorter FDs less explored. We reviewed 263 patients with unruptured intracranial saccular ICA aneurysms treated with FDs from 2013 to 2023. Fifty-five were treated with very short flow diverters (VSFD; 10-12 mm). The primary outcome was complete aneurysm occlusion at 6 months and 1 year, assessed by the Raymond-Roy classification. Secondary outcomes included functional status and retreatment. Complete occlusion rates were 58.2% at 6 months and 70.4% at 1 year in the VSFD group, comparable to the 14-50 mm FD group before and after propensity score matching (PSM). One-year functional outcomes and overall complication rates were similar between groups. The VSFD group had a significantly lower retreatment rate at 4.3% compared to 17.4% in the 14-50 mm FD group (OR 0.21, 95% CI 0.05-0.90, P = 0.04) after PSM. In conclusion, real-world data validate the theoretical concept that VSFDs ensure full deployment and optimal pore density at the aneurysm neck, evidenced by high rates of complete aneurysm occlusion and reduced retreatment rates in our study.

Indexed as

Carotid Artery DiseasesCarotid Artery, InternalEndovascular ProceduresIntracranial AneurysmStentsAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeFD lengthFlow divertorIntracranial ICA aneurysmOcclusionRetreatment

Identifiers

PMID40858662
PMCPMC12381123

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.