ArticleScientific reports2025
Optimized deep learning for brain tumor detection: a hybrid approach with attention mechanisms and clinical explainability.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- YOLO-LS: a novel deep learning framework for brain tumor segmentation in Magnetic Resonance Imaging.Scientific reports · 2026Article
- A minimal-net CNN model for an IoT-based brain tumor detection and monitoring system.Scientific reports · 2026Article
- A Sensor-Oriented Multimodal Medical Data Acquisition and Modeling Framework for Tumor Grading and Treatment Response Analysis.Sensors (Basel, Switzerland) · 2026Article
- Efficient attention-based Ghost-ResNet for brain tumor classification in magnetic resonance imaging (MRI).Frontiers in neuroscience · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain tumor classification (BTC) from Magnetic Resonance Imaging (MRI) is a critical diagnosis task, which is highly important for treatment planning. In this study, we propose a hybrid deep learning (DL) model that integrates VGG16, an attention mechanism, and optimized hyperparameters to classify brain tumors into different categories as glioma, meningioma, pituitary tumor, and no tumor. The approach leverages state-of-the-art preprocessing techniques, transfer learning, and Gradient-weighted Class Activation Mapping (Grad-CAM) visualization on a dataset of 7023 MRI images to enhance both performance and interpretability. The proposed model achieves 99% test accuracy and impressive precision and recall figures and outperforms traditional approaches like Support Vector Machines (SVM) with Histogram of Oriented Gradients (HOG), Local Binary Pattern (LBP) and Principal Component Analysis (PCA) by a significant margin. Moreover, the model eliminates the need for manual labelling—a common challenge in this domain—by employing end-to-end learning, which allows the proposed model to derive meaningful features hence reducing human input. The integration of attention mechanisms further promote feature selection, in turn improving classification accuracy, while Grad-CAM visualizations show which regions of the image had the greatest impact on classification decisions, leading to increased transparency in clinical settings. Overall, the synergy of superior prediction, automatic feature extraction, and improved predictability confirms the model as an important application to neural networks approaches for brain tumor classification with valuable potential for enhancing medical imaging (MI) and clinical decision-making.
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