ArticleNature communications2025
Genetic architecture of a light-temperature coincidence detector.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Supplemental Lighting Enhances Blueberry Fruit Quality and Flavonoid Accumulation Associated withPlants (Basel, Switzerland) · 2026Article
- Genomic Insights into Winter Wheat Breeding for Severely Cold Climates.International journal of molecular sciences · 2026Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Light and temperature variations are inescapable in nature. These signals provide daily and seasonal information, guiding life history determinations across many taxa. Here we show that signals from the PHOTOTROPIN2 (PHOT2) blue photoreceptor combine with low temperature information to control flowering. Plants lacking PHOT2 flower later than controls when grown in low ambient temperature. This phenotype requires blue light, is blocked by removal of NON-PHOTOTROPIC HYPOCOTYL 3 (NPH3), and is recapitulated by removing the transcription factor CAMTA2. PHOT2 and CAMTA2 show non-additive genetic interactions in phenotype and gene expression. Network-based co-expression analysis indicates system-level control of key growth modules by PHOT2 and CAMTA2. CAMTA2 is required for low temperature up-regulation of EHB1, a known NPH3-interacting protein, providing a potential mechanism of temperature information input to the PHOT-NPH3 blue light signaling system. Together these data describe the genetic architecture of environmental signal integration in this blue light-low temperature coincidence detection module.
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Registered trials
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