Evidence map›Paper›PMID 40858509›Full record

ArticleJournal of movement disorders2026

Feasibility and Preliminary Efficacy of Digital Cognitive Training in Parkinson's Disease With Mild Cognitive Impairment: A Pilot Study.

Dongje Lee, Hang-Rai Kim, Yu Jeong Park, Yisuh Ahn, Daeho Lee, Jungyeun Lee, Su Jin Chung, Seung Yeon Kim, Yeji Hwang, Ji Young Yun and 4 more

Abstract read
In one paragraph

Article in Journal of movement disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dongje LeeRowan, Cheonan, Korea.
Hang-Rai KimRowan, Cheonan, Korea.
Yu Jeong ParkDepartment of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Yisuh AhnThe BOM Brain Health Neuropsychology Center & Cognitive Rehabilitation Research Institute, Seoul, Korea.
Daeho LeeDepartment of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Jungyeun LeeDepartment of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Su Jin ChungDepartment of Neurology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Seung Yeon KimRowan, Cheonan, Korea.
Yeji HwangRowan, Cheonan, Korea.
Ji Young YunDepartment of Neurology, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.
Jin Whan ChoDepartment of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kyum-Yil KwonDepartment of Neurology, Soonchunhyang University Seoul Hospital, Seoul, Korea.
Seong-Beom KohDepartment of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Sung Hoon KangDepartment of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.

Funding

Korea National Institute of Health 2022-ER1005-00Korea University Guro Hospital O2208241
6 · The paper itself

Abstract

objectiveCognitive impairment is common in patients with Parkinson's disease (PD), and few pharmacological options are available for treating this condition. We evaluated the effects of a digital cognitive training program (SUPERBRAIN), which was previously shown to be effective in populations at risk of Alzheimer's disease, on cognitive function in individuals with PD.

methodsTwenty-three individuals with PD and mild cognitive impairment (PD-MCI) from four clinics were randomized to the intervention (n=16) or control (n=7) groups. The intervention group completed a 12-week, home-based, tablet-based cognitive training program (25-30 min/day, 7 days/week). Cognitive outcomes were assessed using the Seoul Neuropsychological Screening Battery pre- and post-intervention.

resultsThe adherence rate was 79.36%. The intervention group showed significant improvements in the Seoul Verbal Learning Test (SVLT) delayed recall and the Controlled Oral Word Association Test, while no changes were observed in the control group. Analysis of covariance confirmed greater SVLT improvement in the intervention group (F statistic=7.15, p=0.015, partial η2=0.28).

conclusionSUPERBRAIN is feasible and can improve cognitive function in individuals with PD-MCI.

Indexed as

Digital cognitive trainingMild cognitive impairmentParkinson’s disease

Identifiers

PMID40858509
PMCPMC12885637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.