Evidence map›Paper›PMID 40858501›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

The Somatostatin Pathway Projected from the Basal Forebrain to the Lateral Habenula Promotes Isoflurane Anesthesia Recovery.

Ying Wang, Zhimin Wang, Mao Xu, Jiamin Wang, Shuang Cai, Danxu Zheng, Aichen Tang, Tian Yu, Yuan Wang, Tianyuan Luo and 1 more

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ying WangDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Zhimin WangDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Mao XuDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Jiamin WangKey Laboratory of Anesthesia and Organ Protection of Ministry of Education (In Cultivation), Zunyi Medical University, Zunyi 563000, China.
Shuang CaiDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Danxu ZhengDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Aichen TangDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Tian YuDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Yuan WangDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Tianyuan LuoDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China 407542949@qq.com yusy@zmu.edu.cn yushouyang@foxmail.com.
Shouyang YuDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China 407542949@qq.com yusy@zmu.edu.cn yushouyang@foxmail.com.ORCID 0000-0003-3198-4025

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The basal forebrain (BF) acts as a pivotal relay station in the transmission of arousal signals, projecting to both cortical and subcortical structures. Among its downstream targets is the lateral habenula (LHb), which recent research has implicated in the modulation of sleep rhythms and in mediating the loss of consciousness associated with anesthetic agents. In our study, we utilized optogenetic manipulation to selectively modulate the BF

Indexed as

Anesthesia Recovery PeriodAnesthetics, InhalationBasal ForebrainHabenulaIsofluraneSomatostatinAnimalsElectroencephalographyMaleMiceMice, Inbred C57BLMice, TransgenicNeural PathwaysOptogeneticsAnesthetics, InhalationIsofluraneSomatostatinanesthesiabasal forebrainisofluranelateral habenulapathwaysomatostatin

Identifiers

PMID40858501
PMCPMC12491770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.