Evidence map›Paper›PMID 40858488›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2025

Hearing Loss, Hearing Aid Use, and Neuropsychiatric Symptoms Among Persons Living With Dementia: Findings From NACC.

Ahjeetha Shankar, Emmanuel E Garcia Morales, Jeannie-Marie Leoutsakos, Valerie T Cotter, Milap A Nowrangi, Sevil Yasar, Constantine G Lyketsos, Esther S Oh, Carrie L Nieman

Abstract read
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Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Ahjeetha ShankarJohns Hopkins University School of Medicine (AS), Baltimore, MD.
Emmanuel E Garcia MoralesDepartment of Population Health (EEGM), New York University Grossman School of Medicine, New York, NY; Department of Otolaryngology-Head and Neck Surgery (EEGM), New York University Grossman School of Medicine, New York, NY.
Jeannie-Marie LeoutsakosDepartment of Psychiatry and Behavioral Sciences (JML, MAN, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD; Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease (JML, MAN, SY, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD.
Valerie T CotterJohns Hopkins University School of Nursing (VTC, ESO, CLN), Baltimore, MD.
Milap A NowrangiDepartment of Psychiatry and Behavioral Sciences (JML, MAN, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD; Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease (JML, MAN, SY, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD.
Sevil YasarRichman Family Precision Medicine Center of Excellence in Alzheimer's Disease (JML, MAN, SY, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD; Division of Geriatric Medicine and Gerontology (SY, ESO), Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Constantine G LyketsosDepartment of Psychiatry and Behavioral Sciences (JML, MAN, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD; Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease (JML, MAN, SY, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD.
Esther S OhDepartment of Psychiatry and Behavioral Sciences (JML, MAN, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD; Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease (JML, MAN, SY, CGL, ESO), Johns Hopkins University School of Medicine, Baltimore, MD; Johns Hopkins University School of Nursing (VTC, ESO, CLN), Baltimore, MD; Division of Geriatric Medicine and Gerontology (SY, ESO), Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; Cochlear Center for Hearing & Public Health (ESO, CLN), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Carrie L NiemanJohns Hopkins University School of Nursing (VTC, ESO, CLN), Baltimore, MD; Cochlear Center for Hearing & Public Health (ESO, CLN), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; Department of Otolaryngology-Head and Neck Surgery (CLN), Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: cnieman1@jhmi.edu.

Funding

National Alzheimer's Coordinating CenterU24AG072122 · NIA · UNIVERSITY OF WASHINGTON · PI STEPHENS, KARI A · 2021 to 2025
$45.8M
'T V ASSESSMENT - MEMORY DISORDERED PATIENTS'P50AG005146 · NIA · JOHNS HOPKINS UNIVERSITY · PI BANDEEN-ROCHE, KAREN J. · 1985 to 2019
$37.6M
Research Education ComponentP30AG062422 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Katherine P Rankin · 2019 to 2026
$36.9M
Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Christine S Ritchie · 2019 to 2026
$36.5M
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DOUGLAS R GALASKO · 2019 to 2026
$34.9M
Wisconsin Alzheimer's Disease Research CenterP30AG062715 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Sanjay Asthana · 2019 to 2026
$34.5M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI KEJAL KANTARCI · 2019 to 2026
$33.5M
Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
Utilizing Technology and AI Approaches to Facilitate Independence andResilience in Older AdultsP30AG073104 · NIA · JOHNS HOPKINS UNIVERSITY · PI Alexis Battle · 2021 to 2026
$31.2M
Research Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Margaret Sewell · 2020 to 2026
$31.0M
Yale Alzheimer Disease Research CenterP30AG066508 · NIA · YALE UNIVERSITY · PI STEPHEN M STRITTMATTER · 2020 to 2026
$30.2M
Research Education CoreP30AG066462 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PHILIP L DE JAGER · 2020 to 2026
$30.1M
NIA NIH HHS P20 AG068082NIA NIH HHS P30 AG021334NIA NIH HHS P30 AG062421NIA NIH HHS P30 AG062422NIA NIH HHS P30 AG062429NIA NIH HHS P30 AG062677NIA NIH HHS P30 AG062715NIA NIH HHS P30 AG066444NIA NIH HHS P30 AG066462NIA NIH HHS P30 AG066468NIA NIH HHS P30 AG066506NIA NIH HHS P30 AG066507NIA NIH HHS P30 AG066508NIA NIH HHS P30 AG066509NIA NIH HHS P30 AG066511NIA NIH HHS P30 AG066512NIA NIH HHS P30 AG066514NIA NIH HHS P30 AG066515NIA NIH HHS P30 AG066518NIA NIH HHS P30 AG066519NIA NIH HHS P30 AG066530NIA NIH HHS P30 AG066546NIA NIH HHS P30 AG072931NIA NIH HHS P30 AG072946NIA NIH HHS P30 AG072947NIA NIH HHS P30 AG072958NIA NIH HHS P30 AG072959NIA NIH HHS P30 AG072972NIA NIH HHS P30 AG072973NIA NIH HHS P30 AG072975NIA NIH HHS P30 AG072976NIA NIH HHS P30 AG072977NIA NIH HHS P30 AG072978NIA NIH HHS P30 AG072979NIA NIH HHS P30 AG073104NIA NIH HHS P30 AG086401NIA NIH HHS P30 AG086404NIA NIH HHS P50 AG005146NIA NIH HHS R01 AG057667NIA NIH HHS R01 AG057725NIA NIH HHS R01 AG076525NIA NIH HHS R01 AG079280NIA NIH HHS U24 AG072122
6 · The paper itself

Abstract

objectiveHearing loss is a common comorbidity among persons living with dementia (PLWD), affecting >90% of individuals. Sensory impairments have been associated with an increased risk of neuropsychiatric symptoms (NPS), while hearing aid use may be protective.

methodWe analyzed cross sectional data from the National Alzheimer's Coordinating Center's Uniform Data Set. We estimated the association between functional hearing loss and number or severity of NPS in a negative binomial regression with robust variance adjusting for demographic and clinical characteristics. In the subsample with hearing loss, we estimated the association between hearing aid use and number or severity of NPS. Selection bias for hearing aid use was addressed using nearest neighbor matching (NNM) based on respondent demographic characteristics.

result10,054 participants were included with a mean age of 75 (SD 8) years. 2,416 (24%) self-reported functional hearing loss with 3.4 (standard deviation [SD] 2.5) mean total number of NPS and mean NPS severity of 5.1 (SD 4.9). In fully adjusted models, hearing loss was not associated with more NPS (predicted prevalence difference (PPD):0.09; 95% confidence interval (CI):-0.06,0.25) or more severe (PPD = 0.25; 95% CI:-0.06,0.56) NPS. In PLWD reporting hearing loss, 1,325 (54.8%) reported hearing aid use. After well-balanced matching, in adjusted models, hearing aid use was associated with fewer (PPD:-0.71; 95% CI:-0.93,-0.50) and less severe NPS (PPD:-1.79; 95% CI:-2.23,-1.34).

conclusionHearing aid use may represent an underutilized, nonpharmacological intervention to address NPS. These findings suggest that hearing care may represent a promising nonpharmacological strategy to explore in managing NPS.

Indexed as

DementiaHearing AidsHearing LossAgedAged, 80 and overComorbidityCross-Sectional StudiesFemaleHumansMaleSeverity of Illness IndexUnited Statesage-related hearing lossalzheimer’s and related dementiasneuropsychiatric symptomsnonpharmacological interventions

Identifiers

PMID40858488
PMCPMC12461887

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.