Evidence map›Paper›PMID 40858377›Full record

Observational studyBMJ open2025

Association between subendocardial viability ratio and cardiovascular events: a cohort study in a Chinese community-based population.

Haotai Xie, Fangfang Fan, Lan Gao, Xiangning Zhang, Jia Jia, Yanjun Gong, Yan Zhang

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haotai XieDepartment of cardiology, Peking University First Hospital, Beijing, China.ORCID http://orcid.org/0009-0002-8830-1205
Fangfang FanDepartment of cardiology, Peking University First Hospital, Beijing, China.ORCID http://orcid.org/0000-0001-8351-4821
Lan GaoDepartment of cardiology, Peking University First Hospital, Beijing, China.
Xiangning ZhangDepartment of cardiology, Peking University First Hospital, Beijing, China.
Jia JiaDepartment of cardiology, Peking University First Hospital, Beijing, China.
Yanjun GongDepartment of cardiology, Peking University First Hospital, Beijing, China.
Yan ZhangDepartment of cardiology, Peking University First Hospital, Beijing, China drzhy1108@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSubendocardial viability ratio (SEVR) is an effective indicator for evaluating the balance between myocardial oxygen supply and demand. This study aims to explore the association between SEVR and cardiovascular events and mortality in a Chinese community-based population.

designRetrospective cohort study.

settingAn observational cohort established by Peking University First Hospital across multiple communities in China.

participantsA total of 5927 participants without a history of stroke or myocardial infarction (MI) from a Chinese community-based cohort were enrolled. PRIMARY AND SECONDARY OUTCOME MEASURES: SEVR was measured non-invasively using carotid artery pressure waveforms. Participants were divided into low (SEVR<1.3) and high (SEVR≥1.3) SEVR groups. The endpoints included major adverse cardiovascular events (MACEs), comprising all-cause mortality, stroke and MI. Cox proportional hazards models were used to analyse the association between SEVR and endpoints.

resultsThe mean age of participants was 62.12±7.65 years. Over a mean follow-up of 3.23±0.36 years, 207 (3.49%) participants experienced MACE, including 54 (0.91%) deaths, 134 (2.26%) strokes and 38 (0.64%) MIs. After adjusting for risk factors, each one-unit increase in SEVR significantly reduced the risks of adverse cardiovascular events: MACE decreased by 48% (HR 0.52, 95% CI 0.28 to 0.96), all-cause mortality decreased by 71% (HR 0.29, 95% CI 0.08 to 0.99) and stroke decreased by 57% (HR 0.43, 95% CI 0.20 to 0.91). In participants aged≥65 years, higher SEVR was significantly associated with a reduced MACE risk (HR 0.24, 95% CI 0.11 to 0.53).

conclusionsSEVR was an independent predictor of cardiovascular events in this community-based population. Higher SEVR was significantly associated with lower MACE risk, particularly in older adults.

Indexed as

Cardiovascular DiseasesEndocardiumMyocardial InfarctionStrokeAgedChinaEast Asian PeopleFemaleHumansMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk FactorsCardiologyCardiovascular DiseaseMortalityPUBLIC HEALTH

Identifiers

PMID40858377
PMCPMC12382504

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.