ArticleAsian spine journal2026
Spinal gunshot wounds and infection: a multicenter cohort study.
Article in Asian spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
STUDY
designA multicenter retrospective cohort study. PURPOSE: To analyze the development of infectious complications from civilian gunshot wounds to the spine and their association with the type of prophylactic antibiotics administered and the duration of administration. OVERVIEW OF LITERATURE: Despite the risk for infections following spinal gunshot wounds, no standardized guidelines exist for their management. The limited and low-quality evidence available underscores the need for further research.
methodsThis retrospective cohort study evaluated adult civilian patients (≥18 years) treated for spinal gunshot wounds at Latin American institutions between 2014 and 2022. Demographic, clinical, and injury characteristics, treatment approaches, and infectious complications were analyzed.
resultsAfter exclusions, 292 patients, primarily adult males (n=251, 86.0%) with a mean age of 32.6 years (standard deviation=11), were included. Most injuries affected the thoracic (n=135; 46.2%) and lumbosacral (n=95; 32.5%) spine. Infectious complications occurred in 20 patients (6.8%), including spinal infections (n=3; 1.0%), non-spinal infections (n=6; 2.1%), and wound infections (n=11; 3.8%). Most patients received prolonged antibiotic prophylaxis. The median duration of antibiotic administration was significantly increased in patients with dirty wounds (p<0.001) and high-velocity injuries (p=0.001). However, the duration of antibiotic administration did not influence spinal infection rates.
conclusionsOur findings indicate a low incidence (1%) of spinal infections among patients with spinal gunshot wounds. Prolonged antibiotic use failed to reduce the risk of spinal infectious complications. Standardized guidelines for antibiotic prophylaxis in these injuries remain necessary to optimize care.
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